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NanoAssemblr - Precision Nanosystems Benchtop


Contact: Dmitry Koktysh
ESB 107 - Analytical

Fee Structure

Get Access - Vanderbilt
Get Access - Non-Vanderbilt

NanoAssemblr Benchtop system provides innovative solutions for the discovery, development and manufacture of novel nanoparticles for use in medical research. It’s designed for rapid prototyping of novel nanoparticle formulations - small molecules, peptides and, nucleic acids into lipid, polymer or hybrid nanoparticles. Non-turbulent microfluidic mixing with precise control over fluid flow rates provides a control over nanoparticle assembly. The software enables the control of input mixing parameters for optimizing particle characteristics such as size and encapsulation efficiency. 


  • Microfluidics-based manufacture of novel nanoparticles by controlled nanoprecipitation.
  • Nucleic acid lipid nanoparticles, liposomes, polymer NPs, emulsions, organic/inorganic NPs
  • Isolated fluid path prevents cross-contamination
  • Laminar fluid flow and time-invariant mixing
  • Rapid mixing (<3 ms)
  • <2 min per formulation
  • Prepare 1 to 15 mL nanoparticles / run
  • Flow rate: 1 mL/min – 18 mL/min
  • Syringe compatibility 1, 3, 5, 10 mL
  • “Limit Size” is controlled by nanoparticle composition
  • Heating controller: 20-70 °C, 3 and 1 mL syringes


  • Lipid, polymer particles manufacturing
  • Nanomedicine formulations
  • Manufacturing of genetic medicine
  • DNA and RNA vaccines