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VINSE - Vanderbilt Institute of Nanoscale Science and Engineering

VINSE - Vanderbilt Institute of Nanoscale Science and Engineering
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Ethan S. Lippmann

Associate Professor of Chemical and Biomolecular Engineering
Associate Professor of Biomedical Engineering
Assistant Professor of Neurology

Overview:

The goal of the Lippmann Lab is to model, understand, and ultimately treat neurovascular and neurodegenerative disease. We operate at the intersection of engineering and regenerative medicine, and our projects span many disciplines, including chemical and biological engineering, biochemistry, and neuroscience. To carry out this work, we use a broad range of experimental techniques including human induced pluripotent stem cell differentiation, biomaterials fabrication, genetic engineering, high throughput screening, and molecular selection. We are highly collaborative and enjoy working with other teams at Vanderbilt University to accomplish our goals.

Awards:

• National Science Foundation CAREER Award
• Chan Zuckerberg Initiative Ben Barres Early Career Acceleration Award
• ChBE Award for Excellence in Teaching
• BrightFocus Foundation Research Award
• NARSAD Young Investigator

Selected Publications:

Spatiotemporal control of morphogen delivery to pattern stem cell differentiation in three-dimensional hydrogels. O’Grady BJ; Balikov DA; Lippmann ES; and Bellan LM , CURRENT PROTOCOLS IN STEM CELL BIOLOGY, 7, 1358-1371 , (2020) View Abstract

A Simplified, Fully Defined Differentiation Scheme for Producing Blood-Brain Barrier Endothelial Cells from Human iPSCs. Neal, EH; Marinelli, NA; Shi, YJ; McClatchey, PM; Balotin, KM; Gullett, DR; Hagerla, KA; Bowman, AB; Ess, KC; Wikswo, JP; Lippmann, ES, STEM CELL REPORTS, 12, 1380-1388 , (2019) View Abstract

iPSC-Derived Brain Endothelium Exhibits Stable, Long-Term Barrier Function in Perfused Hydrogel Scaffolds. Faley, SL; Neal, EH; Wang, JX; Bosworth, AM; Weber, CM; Balotin, KM; Lippmann, ES; Bellan, LM, STEM CELL REPORTS, 12, 474-487 , (2019) View Abstract

Spin: an updated miniaturized spinning bioreactor design for the generation of human cerebral organoids from pluripotent stem cells. Romero-Morales AI; O’Grady BJ; Balotin KM; Bellan LM; Lippmann ES; and Gama V, HardwareX, 6, e00084 , (2019) View Abstract