Karen Davis

Everninomicins are a family of naturally produced oligosaccharides, some of which exhibit ribosome-targeting antibiotic activity. Everninomicin A (EVA) was developed into late-phase clinical trials as an antibiotic but eventually pulled due to toxicity concerns. Toxicity was attributed to aggregates in the formulations, likely caused by π-stacking interactions from flanking aromatic… Read More

The American Society for Cell Biology (ASCB) recently announced the formation of Peer Imaging Clusters (PIC) to receive collaborative research grants to pursue novel research projects as part of the PAIR-UP Imaging Science program for Black imaging scientists. Jamaine Davis, PhD Meharry Medical College… Read More

Molecular Operating Environment (MOE) software users can participate in training sessions for small molecule virtual screening, fragment-based drug design and peptide modeling, conformational searching and docking over the next three months. Mauricio Rodriguez, of Chemical Computing Group, will lead the training sessions via Zoom. MOE enables… Read More

Kaitlyn Ledwitch, Assistant Research ProfessorJens Meiler, Distinguished Research Professor Nuclear magnetic resonance (NMR) is an incredibly powerful technique for determining protein structure. A complete dataset of chemical shifts (CS) and nuclear Overhauser effects (NOEs) obtained from NMR can be used to determine structural models of a protein of interest. Read More

John Yang, assistant professor of chemistry, joined the Vanderbilt University in the fall of 2020. He forged his path to Vanderbilt via Nankai University in China, UCLA and MIT with research focusing on theoretical and computational chemistry, chemical biology, physical organic chemistry and enzyme catalysis. John… Read More

Lauren Jackson, PhDBiological Sciences Congratulations to Lauren Jackson, associate professor of biological sciences, on being selected to the 2023 cohort of Chancellor Faculty Fellows along with twelve other recently tenured faculty. The fellows are composed of highly accomplished teachers and researchers from a wide variety of disciplines and… Read More

Chemotaxis is the process of moving in response to one’s environment, and in bacteria, this process is supported largely by flagella. The flagellum is a motility organelle comprised of an elongated filament and various rings, consistent with its role as a rotary motor. One component, the MS-ring, is vital, both… Read More

The Vanderbilt School of Medicine Basic Sciences is launching the Apex Lecture Series to recognize scientists who are at the forefront of sea-change advances in biomedical discovery. The seminars will connect Vanderbilt’s campus scientific community with scientists who are pioneering new fields, new… Read More

In collaboration with the Lee, Mchaourab and Carrasco labs, the CSB is upgrading from four seats of the Molecular Operating Environment (MOE) to a site license that offers unlimited tokens. MOE enables a wide range of molecular… Read More

As the instruction manual of the cell, DNA plays an essential role in development and organism function. Consequently, several mechanisms exist to repair DNA following damage. Oxidants result in structural damage to DNA which are typically repaired via base excision repair (BER). A set of proteins called glycosylases serve to… Read More