Karen Davis
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John Yang appointed to JCTC Early Career Board
John Yang, PhD, Chemistry John Yang, assistant professor of chemistry, was recently appointed to the inaugural Early Career Board (ECB) for the Journal of Chemical Theory and Computation (JCTC). The ECB initiative provides young investigators with guidance and insight into the editorial process as they pursue… Read MoreFebruary 2, 2024
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Eli McDonald presents Karpay Award Seminar January 23
2024 Karpay Award Winner Eli McDonald, of the Meiler and Plate Labs, gives the MBTP/CSB Seminar on Tuesday, January 23, at 12:20pm in 1220 MRB3. Eli was drawn to scientific research from an early age. He studied the molecular dynamics of phospholipid bilayer self-assembly as an undergraduate at Vanderbilt… Read MoreJanuary 19, 2024
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Delving into polymerase α-primase dynamics
In eukaryotes, DNA replication relies on the synthesis of a chimeric RNA/DNA primer by the heterotetrameric polymerase α-primase (pol-prim) enzyme. The primers generated by pol-prim consist of 7-10 ribonucleotides followed by ~20 deoxyribonucleotides and are generated by distinct active sites in the primase and polymerase subunits. Both… Read MoreJanuary 5, 2024
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A new toxin toolkit for C. diff
Top row, L to R: Shannon Kordus, Heather Kroh Bottom row, L to R: Borden Lacy, Ben Spiller Clostridioides difficile (C. diff) is a leading cause of diarrhea and healthcare-associated infections in the United States and recognized as an urgent threat by the Centers for Disease Control. Virulence of C. Read MoreDecember 1, 2023
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Eli McDonald wins Karpay Award
Eli McDonald, Meiler & Plate Labs Congratulations to Eli McDonald, of the Meiler and Plate Labs, for being named the 2024 recipient of The Karpay Award in Structural Biology. “I am truly honored by this recognition,” Eli said. Eli has worked in the Meiler and… Read MoreNovember 10, 2023
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Is DZA the new DNA? Structural and functional studies of a novel artificial pairing system
Xeno nucleic acids (XNAs) are artificial pairing systems that replace the traditional deoxyribonucleic acid (DNA) system present in most organisms. XNAs are of particular interest in the discovery and development of therapeutics as synthetic molecules offer a wider range of metabolic stability, uptake, distribution and binding partners compared to native… Read MoreNovember 3, 2023
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CSB Symposium 2024 speakers confirmed
The CSB invites you to a day of exciting research, collaboration and networking on Thursday, March 28, 2024! CSB Symposium 2024 features talks from preeminent scientists engaged in cutting-edge research. The lineup of speakers includes Nozomi Ando, James Fraser, Jeanne Hardy… Read MoreNovember 2, 2023
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CSB Cryo-EM Directors receive Research Excellence Award
Left to right: Daniel Diermeier, Melissa Chambers, Scott Collier and Candice Storey Lee (Harrison McClary/Vanderbilt) Melissa Chambers and Scott Collier were recently recognized with the Research Excellence Award at the 2023 Fall Staff Assembly. The Cryo-EM co-directors were honored for their research support, which has made a significant impact… Read MoreSeptember 29, 2023
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A glimpse into higher-order mRNP assemblies
In eukaryotic cells, mRNA is transcribed in the nucleus. Protein factors rapidly bind to newly transcribed mRNA to form a messenger ribonucleoprotein (mRNP), which is exported to the cytoplasm for translation. One complex in humans vital for the formation and export of mRNPs is the transcription-export complex (TREX). TREX… Read MoreSeptember 29, 2023
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2024 Karpay Award: Call for applications
The Karpay Award Committee is now soliciting applications for the 2024 Karpay Award in Structural Biology. This award was established in 2010 to commemorate Dr. Anne Karpay, whose studies were focused on membrane protein structural biology under the guidance of Professors Chuck Sanders and Tina Iverson. Dr. Karpay’s… Read MoreSeptember 20, 2023