Karen Davis
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CSB to co-sponsor Apex Lecture on May 22
The Vanderbilt School of Medicine Basic Sciences is launching the Apex Lecture Series to recognize scientists who are at the forefront of sea-change advances in biomedical discovery. The seminars will connect Vanderbilt’s campus scientific community with scientists who are pioneering new fields, new… Read MoreMay 12, 2023
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MOE workshop scheduled for structure-based drug design
In collaboration with the Lee, Mchaourab and Carrasco labs, the CSB is upgrading from four seats of the Molecular Operating Environment (MOE) to a site license that offers unlimited tokens. MOE enables a wide range of molecular… Read MoreMay 12, 2023
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Structural insights into base excision repair
As the instruction manual of the cell, DNA plays an essential role in development and organism function. Consequently, several mechanisms exist to repair DNA following damage. Oxidants result in structural damage to DNA which are typically repaired via base excision repair (BER). A set of proteins called glycosylases serve to… Read MoreMay 5, 2023
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Congratulations: Ben Brown & Alican Gulsevin
Ben Brown, PhD Brown receives NIH funding Congratulations to Ben Brown, research assistant professor in the Meiler lab, on his recent NIH award for his project titled Developing a computational platform for induced-fit and chemogenetic drug design. The goal of the project is to integrate AI and physics-based… Read MoreMay 5, 2023
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Bill Riner sets sail on the trip of a lifetime
Bill Riner, CSB Sr. Systems Administrator Some days you might think to yourself, “I want to retire and sail around the world.” For Center for Structural Biology Sr. Systems Administrator Bill Riner, that day is coming sooner rather than later. On April 28, Bill officially retires from Vanderbilt University—and… Read MoreApril 21, 2023
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Insights into the regulation of Huntingtin-associated proteins
Figure adapted from Diaz Casas et al. (a) Overlay of the ab initio electron map of the CaM-FF3 complex generated from SAXS and the 3D homology model. Black boxes present a close-up view of the two binding sites. CaM and FF3 are colored orange and green, respectively. Huntington’s disease is… Read MoreMarch 31, 2023
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Protein Trafficking: An interactive network of coats, cargos and adaptors – Oh my!
Figure adapted from Xie et al. Model for the interaction between b’-COP, g’-COP, Glo3 and Arf1 (blue, green, red and pink, respectively). Circled regions indicate COPI mutations important for these interactions. Come take a ride along the intracellular highways that are trafficking pathways! Cells use vesicles to transport diverse… Read MoreMarch 24, 2023
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Sanders promoted to Vice Dean of Basic Sciences
Chuck Sanders, BiochemsitryPhoto by Joe Howell Chuck Sanders was recently promoted from associate dean for research to vice dean of the Vanderbilt School of Medicine Basic Sciences by new Dean John Kuriyan. Chuck will continue in the responsibilities that he had been fulfilling… Read MoreMarch 17, 2023
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MBTP/CSB Student Feedback Meeting moved to March 14
Walter Chazin, MBTP Director Molecular Biophysics Training Program (MBTP) Director Walter Chazin will sit down with students to gather feedback on the training program and seminar series. The meeting has been moved Tuesday, March 14, at 12:20pm in 1220 MRB3. A limited number of box lunches will… Read MoreMarch 6, 2023
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CSB co-hosts Discovery Lecture Series speaker
Yifan Cheng, PhD, UCSF and HHMI The Department of Biochemistry and the CSB will host Dr. Yifan Cheng, University of California San Francisco (UCSF), as The Discovery Lecture Series speaker on Thursday, March 9, at 4pm in 208 Light Hall. Dr. Cheng is an investigator of the… Read MoreMarch 6, 2023