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Karen Davis

  • CSHL macromolecular crystallography course

    CSHL macromolecular crystallography course

    Cold Spring Harbor Laboratory (CSHL) is a leading international center for research and education. As part of its mission, each year CSHL organizes 30 advanced technical science courses, with organizers, instructors and participants from all over the world. CSHL is offering a course in macromolecular crystallography October… Read More

    June 10, 2025

  • Call for Nominations: 2025 Vanderbilt Prize Student Scholar

    Call for Nominations: 2025 Vanderbilt Prize Student Scholar

    Nominations for the 2025 Vanderbilt Prize Student Scholar are invited now through June 27, 2025. Candidates for the Vanderbilt Prize Student Scholar are graduate students in biomedical sciences at Vanderbilt (Ph.D. or M.D./Ph.D. track) who have completed the qualifying exam and have at least one year… Read More

    June 10, 2025

  • CSB Spotlight: Prashant Singh, Iverson Lab

    CSB Spotlight: Prashant Singh, Iverson Lab

    Prashant Singh, Senior Research Associate, Iverson Lab Prashant Singh, is a Senior Research Associate in the Iverson Lab. He’s getting used to the spotlight from his recent appearance on the YouTube channel SmarterEveryDay. However, he’s still the down-to-earth Prash, as he’s known… Read More

    May 30, 2025

  • Redefining synaptic architecture: nanoblocks as key organizing units in the postsynaptic density

    Redefining synaptic architecture: nanoblocks as key organizing units in the postsynaptic density

    Cellular function relies on the nanoscale organization of molecular components. Pre-synaptic, post-synaptic and cell adhesion proteins within the synapse are carefully organized in nanostructures to facilitate the transmission of information between neurons, a process which is essential for synaptic plasticity, learning and memory formation. However, the precise structural arrangement of… Read More

    May 9, 2025

  • CSB Research Spotlight: Wankowicz Lab – How protein movement influences function

    CSB Research Spotlight: Wankowicz Lab – How protein movement influences function

    Understanding how proteins get from point A to point B is top of mind for Stephanie Wankowicz, assistant professor of molecular physiology and biophysics. The Wankowicz lab conducts research on how entropy, a measure of the tendency toward disorder or randomness within a system, shifts when a protein… Read More

    April 28, 2025

  • CSB Spotlight: Katherine Stefanski, Sanders Lab

    CSB Spotlight: Katherine Stefanski, Sanders Lab

    Katherine Stefanski, PhD, Sanders Lab Sanders Lab Postdoc Katherine Stefanski’s lab motto might be “a place for everything and everything in its place.” Outside the lab she likes to wreak a bit of havoc in Smashville! That is, when it doesn’t get in the way of a… Read More

    April 25, 2025

  • From activation to repression: decoding the impact of PPARγ ligands on ligand-binding domain conformation

    From activation to repression: decoding the impact of PPARγ ligands on ligand-binding domain conformation

    Nuclear receptors (NRs) are a group of transcription factors that control gene expression in response to endogenous metabolites and synthetic ligands. Ligands bind the C-terminal ligand-binding domain (LBD) of NRs which is widely believed to alternate between transcriptionally active and repressive states and be stabilized upon ligand binding. Various X-ray… Read More

    April 11, 2025

  • CSB Spotlight: Areetha D’Souza, Chazin Lab

    CSB Spotlight: Areetha D’Souza, Chazin Lab

    Areetha D’Souza, PhD, Research Instructor, Biochemistry and Chazin Lab Areetha D’Souza is a research instructor in the Department of Biochemistry and the Chazin Lab. With a diverse scientific background centering on NMR and cryo-EM, she still has time for the finer things in life—especially… Read More

    March 21, 2025

  • CSB Research Spotlight: X-ray Crystallography – Paving the way for ‘hypoallergen’ treatments against peanut allergies

    CSB Research Spotlight: X-ray Crystallography – Paving the way for ‘hypoallergen’ treatments against peanut allergies

    The chart on the left shows the panel of peanut-reacting antibodies that the Smith lab isolated from food-allergic patients, indicating that most of the antibodies bound two peanut proteins, Ara h 2 and Ara h 6. The chart in the middle shows a subset of those antibodies separated… Read More

    March 7, 2025

  • CSB Research Spotlight: Sanders Lab – New mechanisms that cause irregular heartbeat

    CSB Research Spotlight: Sanders Lab – New mechanisms that cause irregular heartbeat

    In a recent collaboration with researchers at Northwestern University, newly-minted PhD Kathryn Butcher (Brewer) and Professor of Biochemistry and Vice Dean of Basic Sciences Chuck Sanders found that, for people with long QT syndrome, a heart condition that causes an irregular heartbeat, a more tailored approach to treatment… Read More

    March 3, 2025