Karen Davis

Doug Kojetin, Biochemistry Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-regulated transcription factor located in the nucleus. Endogenous ligands, such as lipids and fatty acids, bind an orthosteric pocket in the ligand-binding domain (LBD) of PPARγ and function as agonists to activate gene expression related to adipogenesis and insulin sensitization. Read More

PhD student Alexandra Schwartz and Professor Hassane Mchaourab (Molecular Physiology and Biophysics, Center for Applied Artificial Intelligence in Protein Dynamics) developed a methodological blueprint to describe the structure of cell membrane transporters. Read more to learn how the Spectroscopy and AI method provide a unique window… Read More

A newly determined structure from the lab of Yi Ren reveals information about the mRNA export pathway and suggests that herpes viruses could hijack that interaction to infect their host. The new structures also reveal how certain mutations in the protein complex could play a role in cancers. First… Read More

Kathryn R. Brewer, Sanders Lab This article was originally published in The Protein Society’s November 2024 Under the Microscope newsletter. It is published here by permission of The Protein Society and the author. By Kathryn R. Brewer, PhD Candidate in Biochemistry, Sanders Lab A 20-year-old woman waits… Read More

Molecular Operating Environment (MOE) software users can participate in training sessions focused on Antibody Modeling and Protein Engineering applications. The sessions are held at various dates throughout November and cover topics, including, protein engineering and properties, developability, hot spot analysis, antibody modeling, humanization and molecular surfaces. Mauricio Rodriguez, of… Read More

Jens Meiler, Chemistry It’s often the simplest and most informal of invitations that can open a world of endless possibilities and lifelong relationships. That’s how Professor Jens Meiler’s extraordinary scientific journey began in the lab of Nobel Prize winner David Baker. What has he made of the opportunities presented to… Read More

The Meiler lab is leading a multi-institution team that was awarded up to $46 million in funding to drive groundbreaking vaccine research from ARPA-H‘s Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx) program. The funding will support a… Read More

Carterra Inc., the world leader in innovative technologies enabling high-throughput biology, and the Vanderbilt University School of Medicine Basic Sciences announced the addition of the Carterra LSAXT label-free interaction analysis platform to the Center for Structural Biology. Vanderbilt and Vanderbilt University Medical Center researchers… Read More

V-FIRST is hiring a cohort of up to 8 highly-motivated and accomplished early-career researchers. These tenure-track (Assistant Professor level) faculty positions offer an excellent opportunity to contribute to cutting-edge research in one of two areas: 1) Structural Biology & Imaging or 2) Genetic and… Read More

Tina Iverson, Pharmacology Tina Iverson, Louise B. McGavock Chair and professor of pharmacology, received an Innovation Catalyst Fund award for her research project, “Inhibition of Bacterial Chemotaxis as an Antibiotic Potentiator,” which focuses on chemotaxis—a versatile process that allows bacteria to swim toward energy-rich… Read More