Karen Davis

In a recent collaboration with researchers at Northwestern University, newly-minted PhD Kathryn Butcher (Brewer) and Professor of Biochemistry and Vice Dean of Basic Sciences Chuck Sanders found that, for people with long QT syndrome, a heart condition that causes an irregular heartbeat, a more tailored approach to treatment… Read More

In cells, multi-subunit coat protein complexes are responsible for coordinating the transport of transmembrane proteins and lipid cargo between membranes. At the endosome, cargo trafficking is mediated by retromer, a heterotrimer composed of VPS26, VPS29, and VPS35. Retromer serves as a “master regulator”, recruiting machinery to help deform the membrane… Read More

Clay Tydings, Walker and Meiler Labs Teamwork makes the dream work! Clay Tydings, of the Walker and Meiler Labs, thinks collaboration is key to not only furthering his scientific endeavors but also for achieving a personal goal. Meet Clay … What… Read More

Ray Blind, Medicine Inositol phosphates are a family of small metabolites characterized by their different phosphorylation patterns. Inositol hexakisphosphate (IP6), the fully phosphorylated form of inositol phosphate, is found in many organisms and is the most abundant inositol phosphate in animal and plant cells. IP6 serves a wide range of… Read More

Congratulations to Jenny Tran, of the Breann Brown lab, on being named the 2025 recipient of the Dr. Anne Karpay Award in Structural Biology. “It’s such an honor to be selected as the recipient of the Karpay Award,” Tran said. Although she completed a summer… Read More

2025 Anne Karpay Award in Structural Biology Winner Jenny Tran, of the Breann Brown lab, gives the MBTP/CSB Seminar on Tuesday, January 21, at 12:20pm in 1220 MRB3. Although in high school Jenny completed a summer research internship with Howard Hughes Medical Institute Professor David… Read More

Heather Kroh, PhD, Pathology, Microbiology and Immunology Heather Kroh, PhD, is a research assistant professor in the Pathology, Microbiology and Immunology department and currently works in the Lacy lab. With a long-standing dedication to scientific education, she participates in many mentoring and outreach programs,… Read More

Will Wan, Biochemistry Cryo-electron tomography (cryo-ET) is method for determining structure that relies on tilting a microscope sample stage to collect a wide range of sample views. This unique acquisition technique is especially useful for imaging in the context of cells or intact extracellular particles, allowing researchers to study structure… Read More

Doug Kojetin, Biochemistry Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-regulated transcription factor located in the nucleus. Endogenous ligands, such as lipids and fatty acids, bind an orthosteric pocket in the ligand-binding domain (LBD) of PPARγ and function as agonists to activate gene expression related to adipogenesis and insulin sensitization. Read More

PhD student Alexandra Schwartz and Professor Hassane Mchaourab (Molecular Physiology and Biophysics, Center for Applied Artificial Intelligence in Protein Dynamics) developed a methodological blueprint to describe the structure of cell membrane transporters. Read more to learn how the Spectroscopy and AI method provide a unique window… Read More