Computational modeling biomechanics of phonation for surgery planning
In this project, we aim to develop high-fidelity, patient-specific computational models to simulate the biomechanical interaction between glottal airflow and soft vocal fold tissue, i.e., the process of voice production in the larynx. Such computational models will be used to predict the effect of implant on the vocal fold vibration and to help surgeons improve the preoperative design of the implant in Type 1 laryngoplasty, the surgical procedure to treat unilateral vocal fold paralysis. Using evoked rabbit phonation as an animal model, we have developed a combined experimental/modeling procedure to construct and validate a subject-specific simulation tool. Our current effort focuses on advancing the computational tool for clinical applications by addressing practical issues such as model uncertainties.
Workflow of vocal fold construction from imaging data.
Coupled fluid-structure interaction simulation of vocal fold vibration