VISE Summer Instructional Seminar 6.17.21
VISE Research in Progress (RiP)
Date: Thursday, June 17, 2021
Time: Noon admittance, 12:05 p.m. remarks, 12:10 p.m. start
Joshua McCune, PhD Candidate (BME),
Rachel Ping, MS Candidate (BME)
Speaker #1: Joshua McCune, PhD Candidate, Department of Biomedical Engineering
RiP #1: Title: ROS-responsive scaffolds with improved hydrophilicity for diabetic wound repair
RIP #1 Description: More than 6.5 million people suffer from chronic wounds annually, a large majority of which result from diabetes. This work focuses on developing novel synthetic materials for wound healing therapeutics that are responsive to cellular stimuli such as reactive oxygen species (ROS) while optimizing the cellular responses to the material to promote an improved wound healing response. These studies have focused on developing materials of varying hydrophilicity that correlate to enhanced wound healing and have led to developing a next-generation wound healing material to further elucidate the relationship between scaffold hydrophilicity and wound healing responses.
Speaker #2: Rachel Ping, MS Candidate, Department of Biomedical Engineering
RiP #2: Noninvasive Thermographic Imaging: A Novel Method of Diagnostic
RIP #2 Description: Advancements in surgical cardiopulmonary bypass techniques have greatly improved the outcome of morbidity and mortality in a fragile infant population, but the inflammatory cascade that follows such a procedure manifests in a collection of symptoms termed Low Cardiac Output Syndrome (LCOS), which can carry a significant mortality rate in almost a quarter of surgical cases. There is no singular, definitive predictive marker of LCOS to assist in post-operative monitoring and care, which makes monitoring and intervention difficult, expensive, and unreliable. Over the last decade, thermographic imaging has emerged as an inexpensive, reproducible, and reliable tool to provide noninvasive assessment of peripheral perfusion. In an effort to reduce incidence of LCOS, thermographic imaging is deployed in the ICU immediately following surgery to monitor the state of perfusion and to try to predict development of the syndrome on a more rapid time scale than other monitoring methods.