Qualitative Amino Acid Panel

Amino acids, often referred to as the building blocks of proteins, are compounds that play many critical roles in the body. They are needed for vital processes like the building of proteins and biosynthesis of hormones and neurotransmitters. In addition, they can be predictors of outcome in heart failure, hepatobiliary and some cancers, as well as markers for prediabetes (glycine), type 2 diabetes (valine, leucine, isoleucine, phenylalanine and tyrosine) or kidney function (tryptophan-kynurenine ratio).

The CIT has developed a 20 amino acids MS-based assay that can be applied to diverse biological sample types (e.g. plasma, serum, urine, cells or tissue). These analyses are performed with high precision (≤ 5 ppm) and low variability (≤ 10% RSD).

See image below for an extracted ion chromatogram of individual amino acids.