Recent CIT Publications
- Stark RJ, Schrimpe-Rutledge AC, Codreanu SG, Sherrod SD, McLean JA, Krispinsky LT, Lamb FS. ENDOTHELIAL-DEPENDENT VASCULAR REACTIVITY AFTER CARDIOPULMONARY BYPASS IS ASSOCIATED WITH UNIQUE METABOLOMIC SIGNATURES. Shock. 2024 Nov 1;62(5):656-662.
DOI: 10.1097/SHK.0000000000002446 - Mouton AJ, Aitken NM, Morato JG, O’Quinn KR, do Carmo JM, da Silva AA, Omoto ACM, Li X, Wang Z, Schrimpe-Rutledge AC, Codreanu SG, Sherrod SD, McLean JA, Stanford JK, Brown JA, Hall JE. Glutamine metabolism improves left ventricular function but not macrophage-mediated inflammation following myocardial infarction. Am J Physiol Cell Physiol. 2024 Sep 1;327(3):C571-C586.
DOI: 10.1152/ajpcell.00272.2024 - Westland MD, Schrimpe-Rutledge AC, Codreanu SG, Sherrod SD, McLean JA, McClain MS, Cover TL. Taurine modulates host cell responses to Helicobacter pylori VacA toxin. Infect Immun. 2024 Aug 13;92(8):e0022424.
DOI: 10.1128/iai.00224-24 - Pfalzer AC, Shiino S, Silverman J, Codreanu SG, Sherrod SD, McLean JA, Claassen DO. Alterations in Cerebrospinal Fluid Urea Occur in Late Manifest Huntington’s Disease. J Huntingtons Dis. 2024;13(1):103-111.
DOI: 10.3233/JHD-231511 - Schalich KM, Buendia MA, Kaur H, Choksi YA, Washington MK, Codreanu GS, Sherrod SD, McLean JA, Peek RM Jr, Acra SA, Townsend SD, Yan F. A human milk oligosaccharide prevents intestinal inflammation in adulthood via modulating gut microbial metabolism. mBio. 2024 Apr 10;15(4):e0029824.
DOI: 10.1128/mbio.00298-24
See the complete list HERE
Suggested Reading
- Leaptrot KL, May JC, Dodds JN, McLean JA, Ion mobility conformational lipid atlas for highconfidence lipidomics, Nat. Commun 2019, 10:985.
DOI: 10.1038/s41467-019-08897 - Picache JA, Rose BS, Balinski A, Leaptrot KL, Sherrod SD, May JC, McLean JA, Collision cross section compendium to annotate and predict multi-omic compound identities, Chem Sci 2019, 10, 983-993.
DOI: 10.1039/C8SC04396E - Schrimpe-Rutledge AC, Codreanu SG, Sherrod SD, McLean JA, Untargeted Metabolomics Strategies – Challenges and Emerging Directions, Journal of the American Society for Mass Spectrometry 2016, 27:1897.
DOI: 10.1007/s13361-016-1469-y - Patti GJ, Yanes O, Siuzdak G. Innovation: Metabolomics: the apogee of the omics trilogy. Nat Rev Mol Cell Biol. 2012 Mar 22;13(4):263-9.
DOI: 10.1038/nrm3314
Patents
- KL Leaptrot, JC May, JA McLean, METHODS AND SYSTEMS FOR ION MOBILITY AND MASS ANALYSIS. US Patent App. 16/962,744, 2021
- Caprioli R., Wikswo J., McLean J., Skaar E., Norris J.L., Lacy D.B., Sherrod S., Pino J., Gutierrez D., Muszynski N.D., Farrow M. (2020) High-Throughput, Multi-Omics Approach to Determine and Validate De Novo Global Mechanisms of Action for Drugs and Toxins. U.S. Patent No. US10,607,721 B2.
- McLean, J. A., Russell, D. H., Egan, T. F., Ugarov, M. V. and Schultz, J. A. (2010) Multiplex Data Acquisition Modes for Ion Mobility-Mass Spectrometry. U. S. Patent No. US7745780B2.
Useful Links/Resources
- The McLean Group
- Vanderbilt Department of Chemistry
- Center for Quantitative Sciences at Vanderbilt
Our collaborators for advanced statistical modeling and analysis of molecular omics results for basic science, translational, and clinical research projects - Vanderbilt Microbiome Innovation Center (VMIC)
VMIC coordinates and accelerates interdisciplinary scholarship to establish long-lasting resources in microbiome research and education. This effort brings together approximately 300 members (faculty, staff, students) from six Vanderbilt schools to understand, translate, and disseminate the principles that shape host-microbiome interactions, microbial genomics and metabolism, intimate symbiotic relationships, virology, epidemiology, statistical modeling, and applications for precision medicine. - Metabolomics Society
- American Society for Mass Spectrometry
- Metabolomics Quality Assurance and Control Consortium (mQACC)
- Metabolomics Databases/Libraries:
- Open Source Data Analysis Software:
Follow Us