A research project lead by Professor Blakely (Florida Atlantic University) in collaboration with the Center for Innovative Technology (CIT) at Vanderbilt has been investigating the physiological role of the MBLAC1 gene via global, untargeted mass spectrometry analysis. In the serum metabolome the team was able to discover unique differences in primary bile acid biosynthesis and linoleate metabolism between MBLAC1 knock-out and age-matched wild-type mice. Future targeted metabolomics studies are expected to reveal the MBLAC1 substrate and its related neuroprotective effects.

The full, peer-reviewed publication can be found here.