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Synchrotron Access

Beamtime access during the APS Dark Period

Vanderbilt crystallographers have access to macromolecular beamlines through membership in the Life Sciences Collaborative Access Team (LS-CAT) at the Advanced Photon Source of Argonne National Laboratory.

LS-CAT provides a significant amount of beamtime throughout the Dark Period to Vanderbilt researchers via LS-CAT Block Allocation Group proposals to NSLS-II at Brookhaven National Laboratory, Diamond Light Source in the UK, and ESRF in Grenoble, France.

For Dark Period Beamtime, go to The website is continually updated. Check the website each time you want to request time for the most current instructions and information.

Please read the following additional instructions from LS-CAT:

The “arrive to” LS-CAT deadlines for your dewars for each upcoming synchrotron visit are on our home page. There could be a possibility of dewars getting too full to hold all of your crystals for one trip if you have a large number of samples, so please indicate in some way in the Sample Spreadsheet any higher priority samples (some people use background colors in the table, with a legend of what they mean at the top).  Let us know other things you wish to be considered during data collection as well.

Please include a return FedEx label inside your shipping container along with the Dewar Form.

In addition, please send the following information for each of your samples (ESRF is very particular):
Protein/macromolecule name, long/descriptive form
Acronym you would like to use
Species of Origin (e.g., Human, Rat, specific bacterium, etc.)
Expression cells (e.g., E. coli, Insect, CHO cells, etc.) – OR – state if they are chemically synthesized

If you have any questions, please let us know,

Pamela J Focia <>

Joseph Brunzelle <>