The CSB provides expression vectors and technical expertise to assist researchers with large-scale production of recombinant proteins in E. coli. Our Biophysical Characterization Core supports mass photometry, stopped-flow spectrometry, microscale thermophoresis, dynamic light scattering, circular dichroism, fluorescence and microcalorimetry instruments for measuring macromolecular conformation, stability and binding interactions. Access and on-on-one training are available to any interested Vanderbilt researcher.
The mission of the CSB Shared Resources is to aid Vanderbilt researchers in protein production and biophysical characterization. We provide access to specialized reagents, instrumentation, expertise and training.