Brandt Eichman
William R. Kenan, Jr. Chair and Professor, Department of Biological Sciences
DNA Transactions at an Atomic Level
The genetic information encoded within DNA is copied, maintained, and decoded by protein machines. Our laboratory uses X-ray crystallography and other high-resolution structural and biochemical approaches to investigate the molecular details of how these proteins repair damaged DNA and carry out DNA synthesis. One current focus is on the evolution of DNA repair self-resistance mechanisms.