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CSB Cryo-EM Publications

We expect the Principal Investigator and the User to acknowledge the CSB Cryo-EM Facility in research publications arising from their use of the facility. This acknowledgment should include the following or similar “EM data collections were conducted at the Center for Structural Biology Cryo-EM Facility at Vanderbilt University”.

2020 Publications

2019 Publications

2018 Publications

  • Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating.  Sierra-Valdez F, Azumaya CM, Romero LO, Nakagawa T, Cordero-Morales JF.  Journal of Biological Chemistry, 2018 Aug.
  • Multifunctional pan-ebolavirus antibody recognizes a site of broad vulnerability on the ebolavirus glycoprotein. Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, Flinko R, Orlandi C, Carnahan R, Parrish EH, Sevy AM, Bombardi RG, Singh PK, Mukadi P, Muyembe-Tamfum JJ, Ohi MD, Saphire EO, Lewis GK, Alter G, Ward AB, Rimoin AW, Bukreyev A, Crowe JE Jr. Immunity, 2018 Jul.
  • Cryo-EM structure of the cytoplasmic domain of murine transient receptor potential cation channel subfamily C member 6 (TRPC6). Azumaya CM, Sierra-Valdez F, Cordero-Morales JF, Nakagawa T. Journal of Biological Chemistry, 2018 Jul.
  • Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins. Mousa JJ, Binshtein E, Human S, Fong RH, Alvarado G, Doranz BJ, Moore ML, Ohi MD, Crowe JE Jr. PLoS Pathogens, 2018 Feb.
  • A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells. Kroh HK, Chandrasekaran R, Zhang Z, Rosenthal K, Woods R, Jin X, Nyborg AC, Rainey GJ, Warrener P, Melnyk RA, Spiller BW, Lacy DB. Journal of Biological Chemistry, 2018 Jan.

2017 Publications

  • Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface. Kroh HK, Chandrasekaran R, Rosenthal K, Woods R, Jin X, Ohi MD, Nyborg AC, Rainey GJ, Warrener P, Spiller BW, Lacy DB. Journal of Biological Chemistry, 2017 Sep.
  • Peripheral myelin protein 22 alters membrane architecture. Mittendorf KF, Marinko JT, Hampton CM, Ke Z, Hadziselimovic A, Schlebach JP, Law CL, Li J, Wright ER, Sanders CR, Ohi MD. Science Advances, 2017 Jul.
  • Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Anti8body Actoxumab. Hernandez LD, Kroh HK, Hsieh E, Yang X, Beaumont M, Sheth PR, DiNunzio E, Rutherford SA, Ohi MD, Ermakov G, Xiao L, Secore S, Karczewshi J, Racine F, Mayhood T, Fischer P, Sher X, Gupta P, Lacy DB, Therien AG. Journal of Molecular Biology, 2017 Apr.
  • While the revolution will not be crystallized, biochemistry reigns supreme. Takizawa Y, Binshtein E, Erwin AL, Pyburn TM, Mittendorf KF, Ohi MD. Protein Science, 2017 Jan.