Molecular mechanisms of vesicle-mediated cell-to-cell communications in the central nervous system
Our goal is to address fundamental questions in biology by bridging structural biology with cellular and molecular physiology. Using structural biology techniques, including cellular cryo-electron tomography (cryo-ET) combined with optical imaging and electrophysiological methods, we focus on understanding the molecular mechanisms of vesicle-mediated cell-to-cell communication in the central nervous system.
In the long term, we apply knowledge gained from above mechanistic studies to investigate how dysfunction in certain aspects of neurotransmitter release and neuronal development contributes to brain disorders.
The Zhou Lab is looking for outstanding graduate students and postdoctoral fellows. Email Dr. Zhou for more information.