Skip to main content

Biophysical Instrumentation Core Facility

The CSB maintains a variety of instruments for studying the conformation and stability of macromolecules and for measuring the affinity and thermodynamics of biomolecular interactions. To gain access, please fill out the online consultation form.

Microscale thermophoresis:

  • NanoTemper Monolith NT.115
  • Determine binding affinities using fluorescently labeled ligands
  • Equipped with two LED lasers, blue and red
  • MST Guidelines
Circular Dichroism Spectropolarimeter:

Differential Scanning Calorimeter:

Dynamic Light Scattering:


  • Horiba Jobin Yvon Fluoromax-3
  • L-format, single cuvette holder
  • Water bath regulated, magnetic stirring
  • Polarizers
  • Fluorescence Notes
Isothermal Titration Calorimeter:

  • TA Instruments Affinity ITC
  • Installed in February 2020
  • Injection Syringe Volume up to 250 µL
  • Active cell volume of 1.0 mL
  • Operating Temperature Range from 2 °C to 80 °C
  • Fully automated Injection Syringe Cleaning
  • ITC Notes

Information for Users: