Biophysical Instrumentation Core Facility

The CSB maintains a variety of instruments for studying the conformation and stability of macromolecules and for measuring the affinity and thermodynamics of biomolecular interactions. To gain access, please fill out the online consultation form.

Microscale thermophoresis: NanoTemper Monolith NT.115 Determine binding affinities using fluorescently labeled ligands Equipped with two LED lasers, blue and red MST Guidelines
Circular Dichroism Spectropolarimeter: Jasco J-810 CD Peltier temperature control CD Guidelines
Differential Scanning Calorimeter: MicroCal VP-DSC DSC Guidelines
Dynamic Light Scattering: Wyatt DynaPro NanoStar Installed June 2015 DLS Guidelines
Fluorometer: Horiba Jobin Yvon Fluoromax-3 L-format, single cuvette holder Water bath regulated, magnetic stirring Polarizers Fluorescence Notes
Isothermal Titration Calorimeter: TA Instruments Affinity ITC Installed in February 2020 Injection Syringe Volume up to 250 µL Active cell volume of 1.0 mL Operating Temperature Range from 2 °C to 80 °C Fully automated Injection Syringe Cleaning ITC Notes

Information for Users:

• Facility services and fees
• Instructions for remote access to data stored on the network drive
• Access the CSB Instrumentation Core on iLab