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Antonia N. Kaczkurkin

Assistant Professor of Psychology

Antonia Kaczkurkin is an Assistant Professor in Psychology at Vanderbilt University. She received her Master of Arts and Ph.D. degrees in clinical psychology from the University of Minnesota. She completed her APA-accredited clinical internship at Hennepin County Medical Center in Minneapolis, Minnesota. As a postdoctoral fellow at the University of Pennsylvania, Dr. Kaczkurkin was funded by a National Institute of Mental Health (NIMH) Research Supplement to Promote Diversity in Health-Related Research. Dr. Kaczkurkin is currently funded by a K99/R00 Pathway to Independence Award from the NIMH.

 Dr. Kaczkurkin’s research focuses on understanding the neurobiological mechanisms that contribute to the etiology of internalizing disorders. She integrates multimodal measures such as functional magnetic resonance imaging (fMRI), cerebral blood flow, brain anatomy, psychophysiology (e.g., electroencephalography (EEG), startle blink, skin conductance), and behavior to develop a comprehensive understanding of the basic mechanisms underlying anxiety and depressive disorders. Her research aims to:

1) Investigate abnormal brain anatomy and functioning in anxiety and depressive disorders.

2) Understand the neurobiological heterogeneity that exists within internalizing symptoms.

3) Apply our knowledge about these neurobiological differences to improve treatment outcomes.

 

Representative Publications

Kaczkurkin, A. N., Raznahan, A., & Satterthwaite, T. D. (2018). Sex differences in the developing brain: Insights from multimodal neuroimaging. Neuropsychopharmacological Reviews. https://doi.org/10.1038/s41386-018-0111-z

 Nassar,† R., Kaczkurkin, A. N., Xia, C., Sotiras, A., Pehlivanova, M., Moore, T. M., Garcia de La Garza, A., Roalf, D. R., Rosen, A., Lorch, S., Ruparel, K., Shinohara, R. T., Davatzikos, C., Gur, R. C., Gur, R. E., & Satterthwaite, T. D. (2018). Gestational age is dimensionally associated with structural brain network abnormalities across development. Cerebral Cortex. https://doi.org/10.1093/cercor/bhy091

†Denotes shared first authorship and equal contribution

 Kaczkurkin, A. N., Fitzgerald, H., Tyler, J., & Asnaani, A. (2018). The contribution of anxiety sensitivity to obsessive-compulsive and anxiety symptoms in a naturalistic treatment setting. Cognitive Therapy and Research, 42, 661-673. https://doi.org/10.1007/s10608-018-9909-6

 Chang, C., Kaczkurkin,* A. N., McLean, C. P., & Foa, E. B. (2018). Emotion regulation is associated with PTSD and depression among female adolescent survivors of childhood sexual abuse. Psychological Trauma, 10, 319-326. http://dx.doi.org/10.1037/tra0000306

*Denotes primary mentorship

 Asnaani, A., Kaczkurkin, A. N., Benhamou, K., Yarvis, J. S., Peterson, A. L., Young-McCaughan, S., & Foa, E. B, for the STRONG STAR Consortium. (2018). The influence of posttraumatic stress disorder on health functioning in active duty military service members. Journal of Traumatic Stress, 31, 307-316. http://dx.doi.org/10.1002/jts.22274

 Kaczkurkin, A. N., Moore, T. M., Calkins, M. E., Ciric, R., Detre, J. A., Elliott, M. A., Foa, E. B., Garcia de La Garza, A., Roalf, D. R., Rosen, A., Ruparel, K., Shinohara, R. T., Xia, C. H., Wolf, D. H., Gur, R. E., Gur, R. C., & Satterthwaite, T. D. (2017). Common and dissociable regional cerebral blood flow differences associate with dimensions of psychopathology across categorical diagnoses. Molecular Psychiatry. http://dx.doi.org/10.1038/mp.2017.174

 Kaczkurkin, A. N., Zang, Y., Gay, N. G., Peterson, A. L., Yarvis, J. S., Borah, E. V., Dondanville, K. A., Hembree, E. A., Litz, B. T., Mintz, J., Young-McCaughan, S., & Foa, E. B; for the STRONG STAR Consortium. (2017). Cognitive emotion regulation strategies associated with the DSM-5 posttraumatic stress disorder criteria. Journal of Traumatic Stress, 30, 343-350. http://dx.doi.org/10.1002/jts.22202

 Hall-Clark, B., Kaczkurkin, A. N., Asnaani, A., Zhong, J., Peterson, A. L., Yarvis, J. S., Borah, E.V., Dondanville, K.A., Hembree, E. A., Litz, B. T. Mintz, J., Young-McCaughan, S. & Foa, E. B (2017). Ethnoracial differences in PTSD symptoms and trauma-related cognitions in treatment-seeking active duty military personnel with PTSD. Psychological Trauma: Theory, Research, Practice, and Policy, 9, 741-745. http://dx.doi.org/10.1037/tra0000242

 Asnaani, A., Kaczkurkin, A. N., Alpert, E., McLean, C. P., Simpson, H. B., & Foa, E. B. (2017). The effect of treatment on quality of life and functioning in OCD. Comprehensive Psychiatry, 73, 7-14. http://dx.doi.org/10.1016/j.comppsych.2016.10.004

 Kaczkurkin, A.N., Burton, P.C., Chazin, S.M., Manbeck, A.B., Espensen-Sturges, T., Cooper, S.E., Sponheim, S.R., & Lissek, S. (2017). Neural substrates of overgeneralized conditioned fear in PTSD. American Journal of Psychiatry, 174, 125-134. http://dx.doi.org/10.1176/appi.ajp.2016.15121549

 Zandberg, L., Kaczkurkin, A. N., McLean, C. P., Rescorla, L., Yadin, E., & Foa, E. B. (2016). Treatment of adolescent PTSD: The impact of prolonged exposure versus client centered therapy on co-occurring emotional and behavioral problems. Journal of Traumatic Stress, 29, 507-514. http://dx.doi.org/10.1002/jts.22138

 Asnaani, A., Kaczkurkin, A.N., Tannahill, H., & Fitzgerald, H. (2016). Moderators of change in social anxiety during CBT in a transdiagnostic, naturalistic treatment-seeking sample. Journal of Experimental Psychopathology, 7, 655-670. http://dx.doi.org/10.5127/jep.055416

 Kaczkurkin, A. N., Moore, T. M., Ruparel, K., Ciric, R., Calkins, M. E., Shinohara, R. T., Elliott, M. A., Hopson, R., Roalf, D.R., Vandekar, S. N., Gennatas, E. D., Wolf, D. H., Scott, J. C., Pine, D. S., Leibenluft, E., Detre, J. A., Foa, E. B., Gur, R. E., Gur, R. C., & Satterthwaite, T. D. (2016). Elevated amygdala perfusion mediates developmental sex differences in trait anxiety. Biological Psychiatry, 80, 775-785. http://dx.doi.org/10.1016/j.biopsych.2016.04.021

 Kaczkurkin, A. N., Asnaani, A., Hall-Clark, B., Peterson, A. L., Yarvis, J. S., Foa, E. B., & the STRONG STAR Consortium. (2016). Ethnic and racial differences in clinically relevant symptoms in active duty military personnel with posttraumatic stress disorder. Journal of Anxiety Disorders, 43, 90-98. http://dx.doi.org/10.1016/j.janxdis.2016.09.004

 Kaczkurkin, A. N., Asnaani, A., Zhong, J., & Foa, E. B. (2016). The moderating effect of state anger on treatment outcome in female adolescents with PTSD. Journal of Traumatic Stress, 29, 325-331. http://dx.doi.org/10.1002/jts.22116

 Kaczkurkin, A. N., Asnaani, A., Alpert, E., & Foa, E. B. (2016). The impact of treatment condition and the lagged effects of PTSD symptom severity and alcohol use on changes in alcohol craving. Behaviour Research and Therapy, 79, 7-14. http://dx.doi.org/10.1016/j.brat.2016.02.001

 Kaczkurkin, A. N., & Foa, E. B. (2015). Cognitive-behavioral therapy for anxiety disorders: an update on the empirical evidence. Dialogues in Clinical Neuroscience, 17(3), 337-346.

 Kaczkurkin, A. N., & Lissek, S. M. (2014). Generalization of conditioned fear and obsessive-compulsive traits. Journal of Psychology and Psychotherapy: Cognitive and Experimental Psychology, S7(003), 1-7.

 Lissek, S., Kaczkurkin, A. N., Rabin, S., Geraci, M., Pine, D. S., & Grillon, C. (2014). Generalized anxiety disorder is associated with overgeneralization of classically conditioned-fear. Biological Psychiatry, 75(11), 909-915. http://dx.doi.org/10.1016/j.biopsych.2013.07.025

 Kaczkurkin, A. N. (2013). The effect of manipulating task difficulty on error-related negativity in individuals with obsessive-compulsive symptoms. Biological Psychology, 93, 122-131. http://dx.doi.org/10.1016/j.biopsycho.2013.01.001

 

 

 


Honors

Invited participant in the Career Development Institute for Psychiatry (2018-2019)

 NIMH Research Supplement to Promote Diversity in Health-Related Research, National Institute of Mental Health (2017-2018)

 Distinguished Young Scientists in the Field of Neuropsychopharmacology Travel Award Program, American College of Neuropsychopharmacology (2017-2018)

 Outstanding Poster Award, Penn Promotes Retreat 2017: Sex Differences and the Microbiome (2017)

 Merit Abstract Award for Top-Ranking Submissions, Organization for Human Brain Mapping (2017)

 Postdoctoral Fellowship for Academic Diversity, University of Pennsylvania (2014-2017)