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Clinical Science Brown Bag Series: Reyna Gordon
August 26, 2014

Reyna Gordon, Department of Otolaryngology & Vanderbilt Kennedy Center, Vanderbilt School of Medicine

12:10 p.m. Room 316, Wilson Hall

"Who's got rhythm? The surprising link between rhythm and grammar in typical and atypical language development"

Children with grammatical deficits have been reported to show a number of difficulties with linguistic and musical rhythm, such as impairment when using speech rhythm cues to disambiguate syntax or tapping to the beat in music. In addition, data from typical developed adults has shown that the timing of sentences influences syntactic processing. The literature therefore suggests an association between rhythm and grammar, and possible shared underlying brain resources, that have been little studied in children with typical language development. Our study examined the link between musical rhythm perception and linguistic grammar production in six-year-old children with typical language and found a robust association between these seemingly different abilities. Preliminary findings using the same paradigms on children with language impairment will also be discussed. A series of follow-up studies is planned to better understand the mechanisms underlying the association, as well as the potential for music training to improve grammar skills.


CCN Brown Bag Series: Brent Miller
August 27, 2014

The Cognition and Cognitive Neuroscience (CCN) program presents Brent Miller, Department of Psychology (Palmeri Lab), Vanderbilt University

12:10 p.m. Room 115, Wilson Hall

Title and abstract TBA


Neuroscience Seminar: Peter Kaskan
August 28, 2014

Peter Kaskan, Section on Neurobiology of Learning and Memory, LN, NIMH

12:10 p.m. Room 316, Wilson Hall

 

fMRI activation of cortical and subcortical regions in macaque monkeys associated with anticipation and receipt of reward

Cues that have been paired with reward can elicit approach behaviors. These cues are said to acquire incentive salience; the cues themselves are sought as a means of acquiring their associated reward. In an effort to bridge a gap between rodent and human models of reward processing, we developed a behavioral task and fast event-related fMRI paradigm to distinguish BOLD responses to visual cues that predicted reward (anticipation) from responses due to receipt of reward. Monkeys learned to associate images of miscellaneous objects with a high (75%) and low probability (25%) of water reward in choice trials (two cues) and viewing trials (one cue). Monkeys chose high probability cues following two days of training on about 90 percent of choice trials. Monkeys also showed increased licking at the reward delivery spout for high probability cues. Trial start times and reward delivery times were randomized such that BOLD responses due to visual cues could be distinguished from receipt of reward responses. To create a map of reward anticipation, we contrasted fMRI responses from viewing trials of images that had been paired with high probability of reward to those that had been paired with low probability. To create a map of reward receipt, we contrasted responses due to reward delivery to a baseline measurement. In baseline scans, where all cues predicted the same probability of reward, cues that later became paired with a high probability of reward did not elicit greater BOLD responses than cues that later became paired with a low probability of reward. Monkeys showed no choice preferences during baseline scans nor did they demonstrate increased licking. Following training, brain regions responsive to reward anticipation included the dorsal striatum, amygdala, anterior insula, orbital areas 11 and 12, and medial prefrontal area 32. Also, as expected, regions responsive to receipt of reward included the ventral striatum, gustatory cortex, and orbital area 13. Unexpectedly, we identified patches of IT and cortex within the superior temporal sulcus that showed greater BOLD responses to high probability cues than low probability cues. These results corroborate fMRI findings in humans and electrophysiological findings in monkeys demonstrating that the amygdala and striatum are core components of an incentive salience network, and suggest that IT may play a role in representing some aspect of reward predictive visual cues. Experiments designed to test the role of the amygdala in learning from reward feedback and representing reward predictive stimuli are underway.

 


Clinical Science Brown Bag Series
September 2, 2014

NO SPEAKER SCHEDULED THIS DATE

AN INFORMAL MEETING WITH CLINICAL GRADUATE STUDENTS WILL BE HELD

12:10 p.m. Room 316, Wilson Hall


World on Wednesday: Biomedical Research Internships in Asia, Europe, and the United States
September 3, 2014

International Student and Scholar Services would like you to join us at WOW, where Vanderbilt & the community engage in presentations, informal conversations, and topical lectures on global issues. Lunch will be provided.


CCN Brown Bag Series: Sean Polyn
September 3, 2014

The Cognition and Cognitive Neuroscience (CCN) program presents Sean Polyn, Department of PsychologyVanderbilt University

12:10 p.m. Room 115, Wilson Hall

Title and abstract TBA

 


Neuroscience Seminar: Antonia Thelen
September 4, 2014

Antonia Thelen, Vanderbilt Brain Institute (Wallace Lab), Vanderbilt School of Medicine

12:10 p.m. Room 316, Wilson Hall

Title and abstract TBA


Clinical Science Brown Bag Series: Matt Morris
September 9, 2014

Matt Morris, Meharry Medical College

12:10 p.m. Room 316, Wilson Hall

Title and abstract TBA


CCN Brown Bag Series: Joe Lappin
September 10, 2014

The Cognition and Cognitive Neuroscience (CCN) program presents Joe Lappin, Department of Psychology, Vanderbilt University

12:10 p.m. Room 115, Wilson Hall

Title and abstract TBA


Neuroscience Seminar: Rankin McGugin
September 11, 2014

Rankin McGugin, Department of Psychology (Gauthier Lab), Vanderbilt University

12:10 p.m. Room 316. Wilson Hall

Title and abstract TBA


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