May 2026 Issue
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Mathematics Behind Coffer Illusion: Closed-form Energy Analysis, Perceptual Dominance Inequality and Monte-Carlo Validation
This paper introduces a mathematical model explaining why the Coffer Illusion is initially perceived as geometric shapes, revealing the precise visual cues.Md. Rad Sarar Anando, Md. Towkir Ahmmed Rownak | July 29, 2026
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The Addition of Various Metal-Oxide Coatings on g-C3N4 and Its Correlation with Its Photolytic Ability to Degrade Polyvinyl Chloride (PVC) Plastic
Nickel, Iron, Cobalt, and Copper metal-based coatings was added to the photolytic catalyst, graphitic carbon nitride (g-C3N4), in order to react with polyvinyl chloride, so the solvent of the reacted solution could be analyzed through gas chromatography.Paul Hesleitner, Veronica A. Scherer | June 30, 2026
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Differences in Patterns of Atrophy in Alzheimer's Disease and Psychosis
This paper examines the differences in gray and white matter atrophy patterns in neurodegenerative diseases and their impact on cognitive function.Celia T. Ephrem, Faye McKenna | June 30, 2026
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Measuring the Solar Rotation Period Through the Analysis of Sunspots
Measuring sun’s rotational period from sunspots shows differential rotation: longer at higher latitudes, shorter at the equator.Artin Naderi, Koorosh Rokni | June 12, 2026
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Computational design of Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)-Targeted Oncolytic Virus Therapy to In-hibit Angiogenesis in Non-Small Cell Lung Cancer
This study computationally identifies a high-affinity VEGFR2-binding Fab and models its integration into an engineered oncolytic virus to block angiogenesis and enhance targeted therapy for Non-Small Cell Lung Cancer.Gaurav Sharma, Saanvi Yellanki | June 12, 2026
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LARGAL: Learning Latent Representation of Radio Galaxies for Efficient Compression and Improved Classification
This work establishes new state of the art for detection and classification of radio galaxies through a novel machine learning architecture.Aditya Anand | June 12, 2026
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Target-Dependent Performance of Molecular Similarity Metrics in Drug Discovery
This study systematically evaluates the molecular similarity principle across eight protein targets and shows that its predictive power varies by protein family.Apoorva Purohit, Navya Munjal | June 5, 2026
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Qartographer: A Novel Approach to Quantum Chip Design
In this work we present Qartographer, an open-source Python framework for optimizing ancillary control layouts in quantum processors.Adyoth Sural | June 5, 2026
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Cellular Deepfake Engine: A Dual-GAN Framework Redefining Data Generation for Biomedical Imaging AI
This study presents the Cellular Deepfake Engine, a novel generative AI framework designed to produce high-fidelity, biologically plausible microscopy images across three domains: blood cells, nuclei, and cancerous cells.Akshaj Panjnani, Nirupma Singh | June 3, 2026
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In Silico Screening of BiTE Molecule Targeting CD22 and T-Cell Receptor Complex for Acute Lymphoblastic Leukemia
This research presents a fully in silico pipeline for engineering a Bispecific T-Cell Engager by identifying and validating scFv antibodies that target CD22 and the T-cell receptor for acute lymphoblastic leukemia therapy.Gaurav Sharma, Kiruthic Selvakumar | June 3, 2026
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AI Exploration of Non-Linearities in Dark Matter and Supercluster Detection with SRG/eROSITA
Supervised and unsupervised machine learning models are used to find patterns in galaxy cluster and supercluster features.Antonio Rodriguez, Taly Turchin | June 3, 2026
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Optimized Control of HVAC systems using Artificial Intelligence
This study aims to develop a Neural Network (NN)-based system that regulates room temperature by generating command signals for the valve and bypass damper in a traditional HVAC setup, given suboptimal past control data.Mauricio Hernandez, Pattarapon M. Silaporn | June 3, 2026
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Self-Designing Cells: Evolutionary Algorithms Driving Intelligent Virtual Microbial Systems
Using evolutionary algorithms, this work models how virtual genomes self-optimize traits over time, offering insights into adaptation, complexity, and cellular decision-making.Aditya Borele | June 3, 2026
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Student Challenges in Finding Extracurricular Activities: Insights From Testing an AI-Based Discovery System
This study investigates how an AI-enabled agent can address student barriers and enhance participation in high school extracurricular programs.Ethan J. Park, Si Jung Kim | June 2, 2026
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Exoplanet Anomaly Tagging Using Clustered Folded TESS Light Curves
This paper provides a novel, unsupervised machine learning pipeline for exoplanet anomaly classification.Avanija Vangala | June 2, 2026
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Design and Implementation of High Voltage Pulse Generator in Energizing Magnetized Coils
Arduino Module controlled electronic circuits for generating high voltage pulse by utilizing charging/discharging capacitor and relay bank in energizing four pairs of inductive coils.Brian Han | June 2, 2026
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Molecular and Computational Characterization of GLP-1 Receptor–Agonist Binding Mechanisms for Rational Therapeutic Design
This research paper presents a computational pipeline that identifies key GLP-1 Receptor binding determinants and proposes improved liraglutide variants for next-generation weight-management therapies.Gaurav Sharma, Neil Banahatti | June 2, 2026
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The Shifting Drivers of Residential Energy Tax Credit Usage: An Ensemble Machine Learning Approach
This longitudinal machine learning analysis reveals that drivers of residential energy tax credit adoption have shifted over time, making educational attainment a key driver and revealing structural barriers that exclude less-educated households from utilizing these tax incentives.Aritra Ray | June 2, 2026
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AI-Driven Molecular Design and Docking of Ferroptosis Inhibitors for Parkinson's Disease
This study combines AI-driven molecular design with computational docking validation to identify novel ferroptosis inhibitors for Parkinson's disease treatment.Mili E. Mohanty | June 1, 2026
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GITR-Targeted Small Molecules for Cancer Immunotherapy
A computational investigation identifying and evaluating potential small-molecule binding sites on the GITR protein to inform immunotherapy strategies.Anushka Patchigolla, Moustafa Gabr | May 20, 2026
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Brainwaves and Beats: A Study on the Effects of Music on Cognitive Processes
By examining listening patterns and productivity, this study reveals that calm and structured music can support mental focus in students.Moha (Sara) Dole | May 19, 2026
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Spatio-Temporal Change Point Characterization in Tropical Forests using a Hybrid Pipeline
A hybrid pipeline including a modified BFAST, convolutional neural network embeddings and a XGBoost achieving a ~97% accuracy on a synthet-ic tropical-forest time series and classify into 5 major classes.Subharun Mandal | May 19, 2026
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Controllable AI-Driven Chord Generation Using Transformer Language Models
A system that analyzes user MIDI files and generates musically coherent continuations using AI.Justin DeLay, Shashwat Jaipuriar | May 19, 2026
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Quantifying Patient Narratives to Strengthen Longitudinal Assessment in Chronic Pain
This study presents a computational framework that integrates patient narratives with symptom scales using aspect-based sentiment analysis to generate an interpretable longitudinal wellness index for clinical assessment.Arefeh Sherafati, Ishaan Sinha | May 19, 2026
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Caenorhabditis elegans Under the Influence: Testing the Ef-fects of Caffeine and Ethanol on C. elegans Reproduction
Timed exposures to caffeine and ethanol in Caenorhabditis elegans reveal that both reduce reproductive success; chronic caffeine exposure nearly eliminated egg production and viable progeny, while brief peri-ovulatory ethanol exposure increased egg production but sharply reduced embryo viability.Lauren K. Welsh | May 18, 2026
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Applications for a 3D Printed, Handheld, Low-Cost Centrifuge in Separating Pathogenic Bacteria from Biofluids
This study describes the design and testing of a 3D-printed centrifuge for the preparation of saliva samples for disease detection.Andrea K. Locke, J. Quinn Weiler, Luke E. Whitehead | May 18, 2026
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Evaluating the Emotional Salience of Environmental Images Using the Attentional Blink Paradigm
This study assessed the degree of emotional salience elicited by negatively associated environmental images (e.g., pollution) in the Attentional Blink paradigm.Blessing M. Kosia, J. Quinn Weiler, Julia F. Sanders, Marqueze D. Williams II, Menton M. Deweese | May 18, 2026
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Crowdsourced Ligand Design for Selective Inhibition of the KNa1.2 (Slick) Potassium Channel implicated in Developmental Epileptic Encephalopathies
A hybrid strategy of small molecule drug design that combined evolutionary and crowd sourced designs yielded novel synthetically accessible candidate inhibitors of the Kna1.2 channel implicated in developmental epileptic encephalopathies.Jens Meiler, Otto Watson-Brown, Thomas Scott | May 18, 2026
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Smart Compression Sleeve for Tracking and Recovery Monitoring in Knee Rehabilitation
This study validates a low-cost, sensor-based "Smart Compression Sleeve" that successfully quantifies significant deficits in knee flexion (-27.3%) and postural stability (+38.9%) in patients with injuries, proving its value as an objective tool for data-driven rehabilitation.Krshay Venkatesan | May 18, 2026
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Creating a Replicable Methodology for Categorizing Spatial Editing Techniques
This study is a preliminary step to understanding how space is represented in movies - an investigation of spatial reference frames, spatial cues, and conflict between frames and cues that could affect a movie watcher’s perception of space.Daniel Levin, Kathryn Sam, Meg Tennent | May 15, 2026
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Exploring the Use of Gravel Occurrence Data as an Indicator of Large-Scale Fluvial Events in the Bengal Basin
Analysis of gravel occurrence data revealed a sedimentary series in Western Bangladesh that contained evidence of a large-scale fluvial event in the Early Holocene.Farzana Rahmin, R. Charles Tennent, Steven Goodbred | May 15, 2026
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The Influence of Tutor Engagement, Attention, and Positive Emotions on Student Achievement
This study examines the impact that tutor engagement, attention, and emotions have on student reading growth throughout a 6-week tutoring period.Addison C. Cavender, Julia F. Sanders, Laurie E. Cutting, Sarah S. Hughes-Berheim | May 15, 2026
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Advancement of On-Chip Mixing Capabilities for RAPID, a Microfluidic Radiotracer Synthesis Platform
Producing a microfluidic mixing channel for radiotracer synthesis on a lab on chip device.James Rowe, Leon M. Bellan, Mark Mc Veigh | May 15, 2026
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Comprehensive Analysis of Variant Effects, Mutation Spectrum, and Functional Enrichment in Familial Hypercholesterolemia- Associated Mutations
This study conducts a large-scale genomic and bioinformatic analysis of familial hypercholesterolemia-associated mutations, revealing variant con-sequences, functional enrichment patterns, and mutation spectrum trends that inform precision gene therapy development.Nikhil Puttamraju | May 15, 2026
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Utilizing Topology Optimization and Additive Manufacturing to Increase Accessibility of Highly Capable UAVs
This project shows how Topology Optimization and 3D Printing can reduce drone weight without sacrificing strength, opening the door to more capable and accessible drones.Ashvin Oli, Duc Tien Nguyen, Ravindra Duddu, Shubh Patel | May 15, 2026
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A Token-Level Framework for Quantifying ChatGPT’s Environmental Impacts and a Browser-Based Intervention for Reducing Prompt Resource Use
This study models the water and energy consumption of large-language model inference at the token level and evaluates a Chrome extension that provides real-time eco-feedback to improve user prompt efficiency.Sahil Parasharami | May 15, 2026
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Regulation of the PPARꝩ Pathway using Antagonists and In-verse Agonists across 2D and 3D Models
Utilizing the peroxisome proliferator-activated receptor gamma pathway (PPARꝩ) for immunotherapy in lung cancer models.Amanda Linkous, Jing Hao, Mary Kate Macedonia, Parker Nunnery | May 15, 2026
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Expression and Purification of a Subtilin spaS RiPP Precursor in E. coli
This project attempts to produce the subtilin precursor SpaS in E. coli to support new antibiotic development.Allison S. Walker, Brithany Navarro Padilla, Srujan Vadlamudi | May 15, 2026
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Clumping Properties of Cat Litter made from Diatomaceous Earth, Bentonite and Wheat Flour Blends
This work deals with the synthesis of cat litter material using sustainable materials and testing their properties.Pratham (Pat) Naik | May 15, 2026
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Study of Low Endotoxin Recovery and Its Reversal Strategies
Low Endotoxin Recovery, a false negative in endotoxin testing, was studied comparatively and for viable solutions.Fedor Myshkin | May 15, 2026
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A Machine Learning Framework for Predicting Speech Outcomes in Cochlear Implant Recipients Using Genetic Markers
This study develops an AI-based Random Forest framework that integrates genetic variants and demographic data to accurately predict speech outcomes after cochlear implantation, supporting personalized prognosis and rehabilitation strategies.Navya Mrig, Nirupma Singh | May 15, 2026
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Resurrecting the Dead-Cone: EEC Analysis of the Dead-Cone in Simulated proton-proton Collisions
An investigation of the Dead-Cone effect in proton-proton collision simulations using the Energy-Energy Correlator.Benjamin N. Kimelman, Hudson H. Mills, Rithya Kunnawalkam Elayavalli | May 15, 2026
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Heavy Metal Concentration Changes in Sediment Along the Cumberland River as it Flows Through Nashville and Seasons Change
A waterway study looking at heavy metal concentrations in the Cumberland River and how those concentrations change when moving through farmland to an urban environment (Nashville).Immanuel Ojetola, Madeleine E. McLean, Margaret Tennent, Mary Li, Rebekah Stanton | May 15, 2026
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Disability Attitudes and Policy Perceptions in China and the United States: A Cross-National Survey
The paper examines China–United States attitudes toward disability, finding stronger medical-model views in China, greater United States support for equal employment, and disabled Chinese respondents ranking inclusive education as the most effective awareness strategy.Cynthia Dai | May 15, 2026
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Utilizing Salt Accumulation and Organic Carbon as Proxies for Exposure Age Dating in Beacon Valley, Antarctica
An overview of investigating whether salt deposits and organic carbon traces can reveal the environmental history and surface exposure duration of Beacon Valley.Dan J. Morgan., Isabel Lopez-Jarquin, R. Stanton | May 14, 2026
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Linking Early Life Adversity to Epigenetic Change: A Meta-Analysis of DNA Methylation as a Molecular Memory of Childhood Trauma.
DNA methylation is an epigenetic mechanism that uncovers methylation patterns associated with adversity type, timing, and participant de-mographics.Amanda Lea, Mary M. Li, Rachel Petersen | May 14, 2026
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The Effect of Wetland Restoration on Soil Health
Test of 6 sites, 3 restored and 3 not yet restored, pH, Salinity, and growth effect to determine the effect of restoration on soil health.Collin Finnan, Ryan M. Leung | May 14, 2026
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Female Zebra Finch (Taeniopygia guttata) Preference Test of Male Courtship Song Complexity
An operant preference test was designed to assess female zebra finch preferences towards male courtship song characteristics.Darra Boyer, Nicole Creanza, Noemi S. Ledeczi, Ximena León Du’Mottuchi | May 14, 2026
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The Impact of Synonymous Mutations on the Processing of the Foot-and Mouth Disease Virus Capsid Precursor Protein
This research project aims to study the effects of synonymous mutations on the 3cpro interactions with proteins in the assembly of the FMDV capsid.Blessing Kosia, Lars Plate, Molly Sullivan | May 14, 2026
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An Affordable Dynamic Penetrometer for Soil Resistance and Compaction
The creation of a cost-effective device to measure soil compaction.Hana E. Kajihara, Vishesh Kumar | May 14, 2026
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An Evidence-Based Wearable Intervention to Improve Sun-Safety Awareness and Support Overall Cognitive Well-Being
This study investigates how a wearable UV-monitoring intervention can improve sun-protection habits, skin-health awareness, and understanding of vitamin D among adolescents.SJ Kim, Yerim (Pepper) Jung | May 14, 2026
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Gait-Based Evaluation of Zebrafish Spinal Cord Regeneration
Develop and validate a non-lethal, functional methodology for measuring spinal cord regeneration after injury that matches the accuracy of cellular histology while increasing experimental throughput.Nicolas Noel, Valentina Cigliola, Violet R. Hansen | May 14, 2026
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Investigating the Role of NCAM-1 and Profilin-2 in Synaptic Re-modeling During Neural Development in C. elegans
This study examines how proteins, Profilin-2 and NCAM-1, play a role in regulating the synaptic remodeling process in restructuring neurons during neural development in C. elegans, offering insight into intracellular mechanisms that shape functional neural circuits.Casey Gailey, David M. Miller III, Norvana Hanna | May 14, 2026
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Reference-Point Framing and Future Savings: How Anchoring Bias Influences Saving Intentions among Students
This study carries out an empirical analysis on a randomized experiment carried out on high school students to investigate the role of anchoring bias on decision making and how other mediators (such as financial literacy) can mitigate this effect.Ayah Abdin, Panshul Gupta | May 14, 2026
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Bridging the Gap: Testing Auditory Vignettes as a Means to Reduce Polarization in American Politics
Auditory vignettes were found to elicit emotions in a political context, but did not reduce the polarization that plagues American politics.W. Paxon Garner | May 14, 2026
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The Effect of a Y-Splitter on the Scale Up of Microsphere Formation
Exploring the difference in the formation of microspheres between a Y-splitter and a Flow-focusing microfluidic device.Emmanuel J. Foster, Jamey D. Young, Rachel K. Moen | May 14, 2026
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Using Principal Component Analysis to Investigate Changes in the North American Dipole in Future Simulations
Climate models were used to predict the effects of different levels of climate change on the North American climate patterns.Husile Bai, Marcos R. Dedman Szendrey | May 14, 2026
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Anionic Phospholipids flip by Neo1 regulates Golgi association of Arf-GEF Gea2
This project investigates how the Golgi flippase Neo1regulates protein trafficking by controlling the localization of the Arf-GEF Gea2 through PI4P lipid flipping.Bhawik K. Jain, Briana N. Markham, Todd R. Graham, Zaniya Crite-Cotton | May 14, 2026
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Coupling of IL-1β and Collagen II Targeting Antibodies using the SpyMask System
A bispecific protein designed to inhibit IL-1β while targeting type II collagen to localize anti-inflammatory therapy in osteoarthritis.Jonathan M. Brunger*, Prasamsha Chamlagai, Rebecca L. Shattuck-Brandt, Zachary M. Eidman | May 14, 2026
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The Fehu Function ᚠ(d) and Exponential Equality
An exposition and analysis of the Fehu Function, its properties, and its place in the realm of mathematics.Caleb D. Anderson | May 14, 2026
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Toward Expansion of Biological Plastic Recycling: In Silico Optimization of a Polyurethane-Degrading Metagenomic Urethanase
An artificial intelligence–driven user-friendly enzyme-engineering workflow accelerated the optimization of a metagenomic polyurethane-degrading urethanase.Malya Chakravarty, Moul Dey | May 14, 2026
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Using Fluorescence Resonance Energy-Transfer to Observe DNA Hybridization
Monitoring DNA hybridization with FRETAbigail Anderson, Alyssa Gonneville, Jason Abercrombie, Rajan Lamichhane, Sriram Tiruvadi Krishnan | May 14, 2026