Craig Duvall

As a practicing medical oncologist specializing in gastrointestinal (GI) cancer, understanding the specific genetic mutations, fusions, rearrangements, and other alterations driving the cancer can potentially lead to targeted treatments as alternatives to traditional chemotherapy. During my oncology fellowship training, I was fortunate to join Professor Craig Duvall’s lab, which specialized… Read More

On October 13, 2025, the VINSE Fall Faculty Celebration took place to honor and celebrate the remarkable achievements of our community. This annual event not only highlighted individual accomplishments but also fostered a sense of camaraderie among colleagues. WELCOME TO VINSE Andrea Locke | Bryant Spreine… Read More

VINSE is excited to announce that Alexander (Alex) Sorets is the recipient of the 2025 VINSE Best Collaborative Publication Award. Alex’s capstone publication, published in Nucleic Acids Research, represents a landmark study in brain drug delivery that brought together an extraordinary range of collaborations across… Read More

Patricia Poley Biomedical Engineering Craig Duvall Research Group Reactive oxygen species (ROS) are chemicals that contain oxygen and are chemically reactive and unstable due to their possession of an unpaired electron. Common ROS species in the body include hydrogen peroxide and superoxide anions. At low levels, ROS exist… Read More

The Vanderbilt Institute of Nanoscale Science and Engineering (VINSE) National Science Foundation (NSF) Research Experience for Undergraduates (REU) will onboard our 13th cohort of undergraduate researches on Monday, 26, 2025. Since the VINSE NSF-REU program started in the summer of 2011, VINSE has hosted 145 students. Of these students 95%… Read More

Congratulations to the winners of the 2024 VINSE NanoDay! Poster Competition! The 24th annual Nanoscience & Nanotechnology Forum Welcomed over 250 registered participants, representing 24 departments at Vanderbilt and partner institutions and 14 of industry collaborators.  A total of 66 posters were presented, highlighting the wide range… Read More

“Non-Viral In Vivo Delivery of CRISPR-Cas9 using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles” published in ACS Nano, selected as VINSE Spotlight Publication. This research, led by Biomedical Engineering Prof. Craig Duvall and his 2023 PhD graduate Brock Fletcher, was recently published in ACS Nano. This interdisciplinary project involved… Read More

Craig Duvall, Cornelius Vanderbilt Professor, Department of Biomedical Engineering; Professor, Ophthalmology and Visual Sciences; Professor, Chemical and Biomolecular Engineering The central dogma of biology is that genomic DNA encodes for messenger RNA (mRNA), which is then translated into proteins. Proteins are the fundamental units that drive the functions… Read More

DISSERTATION DEFENSE Isom Kelly III, Biomedical Engineering *under the direction of Dr. Craig Duvall “Developing Endosomolytic Polymer Porous Silicon Nanocomposites For Delivery of Diverse Gene Therapies” Wednesday, March 23, 2022 1:15PM | 5211 SC Intracellular-acting biologics hold significant promise as genetic and other modes of human therapy, to… Read More

Spring Newsletter 2022 graduate student research highlights:   Ella Hoogenboezem, 5th year graduate student in the Duvall lab Short interfering RNA (siRNA) is a powerful gene silencing platform that has the potential to silence tumor-driving genes. However, siRNA medicines for tumor delivery have remained clinically elusive. In… Read More