NIH
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New target for chronic kidney disease
Craig Brooks and colleagues have identified a mechanism of kidney fibrosis progression, suggesting a potential new angle for treating chronic kidney disease. Read MoreJanuary 31, 2019
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Destructive ‘telegrams’ in asthma
Heather Pua and colleagues have identified the source of cellular signals that may play a role in triggering an asthma attack. Read MoreJanuary 31, 2019
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Study finds unique form of chronic sinusitis in older patients
Older patients with a diagnosis of chronic sinusitis have a unique inflammatory signature that may render them less responsive to steroid treatment, according to new research led by Justin Turner. Read MoreJanuary 18, 2019
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DNA’s on/off switch
Walter Chazin and colleagues have identified how a chemical "switch" in DNA primase, an enzyme essential to the replication of our genomes, works in order to hand off genetic information to the next enzyme. Read MoreJanuary 18, 2019
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Signals from the “conveyor belt”
Carlos Lopez, Tina Iverson and Vsevolod Gurevich propose that a conveyer belt best describes the mechanism by which cellular signals are handed off from enzyme to enzyme in the brain. Read MoreJanuary 18, 2019
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Building a pancreas
Ken Lau and Guoqiang Gu have identified a critical biomarker in determining how a pancreatic progenitor cell will develop. Read MoreJanuary 17, 2019
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Research explores link between stem cell transplant, diabetes
Brian Engelhardt is studying why as many as 50 percent of stem cell transplant recipients develop diabetes. Read MoreJanuary 17, 2019
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Pain relievers a risk for C. diff?
David Aronoff and colleagues report an increased risk of the serious gastrointestinal infection C. diff following the use of NSAID pain relievers. Read MoreJanuary 17, 2019
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Trans-institutional team documents potential new treatment path for breast cancer
A team led by biomolecular engineer John Wilson and cancer biologist Rebecca Cook have found a way to trigger an immune response that targets breast cancer cells. Read MoreJanuary 16, 2019
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Bile acids mediate metabolic benefits of weight-loss surgery
A team of Vanderbilt investigators has pinpointed the role of bile acids and a specific signaling pathway in the positive metabolic effects of weight-loss surgery. Read MoreJanuary 10, 2019