NIH

Jeffrey Rathmell and colleagues show that a drug that inhibits glutamine metabolism — currently in clinical trials as an anticancer agent — might also be useful as a treatment for inflammatory and autoimmune diseases. Read More

This work was the foundation for an NSF grant to interrogate how the Rif1 protein controls DNA replication. Read More

James Patton and colleagues have demonstrated how colon cancer cells transmit genetic data to other cells. Read More

A new link between a support protein within the brain's white matter and known Alzheimer's biomarkers discovered by Angela Jefferson and colleagues bring researchers a step toward earlier and more precise detection of neuropathology underlying cognitive impairment that may lead to new targeted therapies Read More

Raymond Harris, Ming-Zhi Zhang and colleagues suggest pathways activated by the epidermal growth factor receptor may be promising targets for treating diabetic kidney disease. Read More

New findings by Dawn Newcomb and colleagues suggest an explanation for why women are more prone to asthma than men. Read More

Research led by Sanjay Mishra, and colleagues suggests modular sHSP architecture contributes to the ability of heat-protective proteins to serve as chaperones for a range of unfolded proteins. Read More

Loss of a protein that regulates mitochondrial function can greatly increase the risk of a heart attack, report Eric Gamazon, Sandra Zinkel and graduate students Christie Salisbury-Ruf and Clinton Bertram in new research. Read More

The hidden lives of medical biomarkers are the focus of a recent study in Nature Communications by Jonathan Mosley. Read More

Reyna Gordon has received a NIH Director’s New Innovator Award of $2.3 million for her project, “Biomarkers of Rhythmic Communication: Integrating Foundational and Translational Approaches.” Read More