NIH
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Indicators of despair rising among Gen X-ers entering middle age
In 2016, a surprising decline in life expectancy was ascribed to "deaths of despair" among working-class middle-aged white men displaced by a changing economy. However, new research shows indicators of despair are rising among Americans approaching middle age regardless of race, education and gender. Read MoreApril 15, 2019
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How bugs overcome host defenses
Eric Skaar and colleagues have figured out how a common bug responsible for ventilator-associated pneumonia responds when starved of zinc, a metal it needs to survive, which may lead to new therapeutic targets for the dangerous infection. Read MoreApril 12, 2019
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Discovery aids search for cancer biomarkers
A report by researchers at Vanderbilt University Medical Center has shattered conventional wisdom about how cells, including cancer cells, shed DNA into the bloodstream. Read MoreApril 12, 2019
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The arrestin-GPCR connection
Vsevolod Gurevich and colleagues have discovered new insights into arrestin proteins, which turn off a cell's environmental message "inbox." Read MoreApril 12, 2019
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Pathways of radiosensitization
Austin Kirschner and colleagues are learning more about how the cancer drug enzalutamide combines with radiation therapy to treat difficult prostate tumors. Read MoreApril 12, 2019
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Drug interaction causes hypotension
A commonly used muscle relaxant can cause severely low blood pressure in patients already taking a CYP1A2 inhibitor, such as ciprofloxacin, find Cecilia Chung and colleagues. Read MoreApril 4, 2019
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Cardiac dysfunction in Duchenne’s
Jonathan Soslow and colleagues have found more clues to why people with Duchenne muscular dystrophy are at risk for a certain kind of heart problem. Read MoreApril 4, 2019
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Cancer prevention drug also disables H. pylori bacterium
A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered. Read MoreMarch 28, 2019
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Study aims to predict treatment response in epilepsy patients
Vanderbilt researchers are on a quest to develop early biomarkers of treatment outcomes for patients with temporal lobe epilepsy based on their individual brain networks. Read MoreMarch 14, 2019
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Reprogramming cells for kidney repair
Lauren Woodard and Matthew Wilson have discovered a way to reprogram adult human kidney cells into cells similar to those that form during embryonic development, which could lead to new kidney disease treatments. Read MoreMarch 14, 2019