Zebrafish

Ela Knapik still remembers the first zebrafish she saw under a microscope—two days old, no bigger than an eyelash, tail wiggling, heart visibly beating. That was more than 20 years ago during her search for a postdoc position. That tiny fish has held her attention ever since and helped unravel many of the biological mysteries she has published about during her professional career. Read More

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms. Read More

According to a new study, the tiny zebrafish may hold the secret to regenerating damaged retinas in humans. Read More

Studies of alpha-B crystallin in zebrafish could ultimately lead to improved treatment for cataracts and heart disease. Read More

Research into retinal regeneration in zebrafish has identified a signal that appears to trigger the self-repair process, raising the possibility of inducing retinal repair in human eyes. Read More

The hormone leptin regulates glucose balance, but not fat stores, in zebrafish. Read More

Vanderbilt investigators demonstrate that a certain eye lens protein is evolutionarily conserved between zebrafish and rat, suggesting that zebrafish can be used as a model system to understand eye lens disorders such as cataracts. Read More

Using revolutionary CRISPR technology, Vanderbilt investigators have developed a fast and simple method to simultaneously turn off multiple genes in order to study complex diseases. Read More

A zebrafish model of a rare genetic disease has revealed an unexpected regulatory pathway for cholesterol absorption and processing. Read More

Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer. Read More