Zebrafish
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Tiny model of diabetes
Vanderbilt University researchers have created a zebrafish model of skeletal muscle insulin resistance that could help improve diabetes treatment. Read MoreFebruary 20, 2015
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Targeting tumor “supply lines”
A metabolic enzyme plays a crucial role in vascular development and may be a good target for cancer therapies. Read MoreDecember 18, 2013
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Fishing for new anti-cancer drugs
Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug. Read MoreSeptember 18, 2013
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Model for MADD mitochondrial disease
A zebrafish model of a severe mitochondrial disease will be useful for developing new therapeutic approaches. Read MoreJuly 11, 2013
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Setting traps to probe gene function
A new method for creating genetic mutations that can be activated at certain times or in specific tissues will enable studies to probe gene function. Read MoreOctober 18, 2012
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New tool hooks heart failure drugs
A new screening tool – using glowing fish embryos – could identify therapeutics for myocardial hypertrophy and heart failure. Read MoreApril 6, 2012
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Fishing for heart attack repair tools
Managing myocardial infarction – and the resulting heart failure – remains a clinical challenge. To search for chemicals that can stimulate cardiac muscle cell production, Vanderbilt Institute of Chemical Biology investigators led by Tao Zhong, Ph.D., Terri Ni, Ph.D., and Eric Rellinger, M.D., turned to a novel drug discovery tool:… Read MoreJanuary 5, 2012
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Clues to skeletal form in ‘feelgood’ fish
Ela Knapik, associate professor of medicine, and colleagues are using zebrafish to explore the molecular and cellular mechanisms that cause birth defects of the face and skeleton. Read MoreDecember 16, 2011
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Fishing for a new model of tuberous sclerosis complex
A zebrafish model of the genetic disease tuberous sclerosis complex will speed new discoveries. Read MoreApril 27, 2011