NIH
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Increased cell permeability may protect from colitis
Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation. Read MoreApril 25, 2014
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New view of neurotransmitter transport
Dynamic measurements of the bacterial leucine transporter shed light on the transporters that play roles in neuropsychiatric and addiction disorders. Read MoreApril 24, 2014
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Nutrient-absorbing surface’s assembly revealed: study
Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens. Read MoreApril 17, 2014
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Channel drug restores glucose balance
A new compound that activates potassium channels could be used to treat disorders of glucose homeostasis. Read MoreApril 16, 2014
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Anthrax bacteria’s signaling systems
Vanderbilt researchers have identified a new signaling system that anthrax bacteria uses to infect its host. Read MoreApril 15, 2014
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Myelin junctions key to conduction
A protein in the myelin coating on nerves helps form a “seal” that enables effective nerve conduction; loss of the protein causes inherited neuropathies. Read MoreApril 11, 2014
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Matrix remodeling and insulin resistance
The extracellular matrix that surrounds cells plays a role in the development of insulin resistance. Read MoreApril 10, 2014
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Development and disease in the aorta
Smooth muscle cells that line the aorta differ in development but not in the adult, a finding that has implications for understanding aortic development and disease. Read MoreApril 2, 2014
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E-records shed light on drug response
Electronic medical records linked to DNA biobanks are a valid resource for defining and understanding the genetic factors that contribute to drug response. Read MoreMarch 31, 2014
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Mapping brain circuitry
Vanderbilt investigators have used two types of neuroimaging to establish a “map” of connections for a brain region important in anxiety and addiction. Read MoreMarch 28, 2014