NIH

New views of how transporters move molecules across cell membranes are key to understanding how these proteins impact tumor cell drug resistance and inherited diseases such as cystic fibrosis. Read More

Virus-like particles containing a protein from human metapneumovirus are a promising vaccine candidate for this respiratory virus. Read More

Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer. Read More

The contractile machinery inside tumor cells increases invasive properties, suggesting it might be a good target to inhibit cancer cell spread. Read More

The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion. Read More

A particular anti-arrhythmia drug provides a targeted treatment for certain forms of atrial fibrillation. Read More

Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage. Read More

A novel PET imaging probe detects tumor cell death in vivo and could be useful for personalizing cancer medicine. Read More

A genetic variant is associated with toxicity of the chemotherapy drug melphalan, and could guide individualized dosing for the medication. Read More

Understanding how chikungunya virus binds to and enters cells offers a new target for antiviral medications. Read More