NIH
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A “CRISPR” way to study disease
Using revolutionary CRISPR technology, Vanderbilt investigators have developed a fast and simple method to simultaneously turn off multiple genes in order to study complex diseases. Read MoreJune 11, 2015
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Study identifies C. diff toxin receptor, suggests new treatment approaches
Vanderbilt University investigators have identified a cellular receptor for a toxin from Clostridium difficile (“C. diff”) — the leading cause of hospital-acquired diarrhea in the United States. Read MoreJune 4, 2015
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Research at U.S. academic medical centers faces threats to sustainable support
Unstable federal research funding and reductions in health care revenue for academic medical centers threatens to undermine the nation’s biomedical research enterprise, and in turn clinical medicine, which the nation needs now more than ever. Read MoreMay 28, 2015
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Preventing early pregnancy complications
The enzyme alkaline phosphatase may provide a new therapeutic option for women at high risk of pregnancy complications due to bacterial toxin exposure. Read MoreMay 20, 2015
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Boosting cell-based heart repair
A metabolic change in adult stem cells makes them less “fit” for regenerative heart therapies, suggesting that strategies to prevent this response may boost the therapeutic usefulness of the cells. Read MoreMay 15, 2015
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Insights on lysosomal storage diseases
A novel mechanism could point to new therapies for a group of inherited diseases that share pathological features. Read MoreMay 14, 2015
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Locating the brain’s SAD center
Vanderbilt biologists have localized the seasonal light cycle effects that drive seasonal affective disorder to a small region of the brain called the dorsal raphe nucleus. Read MoreMay 7, 2015
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Neurofibromin fine-tunes bone growth
The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered. Read MoreMay 6, 2015
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New player in neuronal communication
Vanderbilt researchers have discovered a novel mechanism for the development of dendritic spines – sites of nerve cell communication. Read MoreMay 1, 2015
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RNA defects in multiple sclerosis
Vanderbilt researchers have discovered that profound defects exist in the integrity of structural RNA molecules in patients with relapsing remitting multiple sclerosis. Read MoreApril 30, 2015