NIH
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Potential target for lung cancer therapy
The glutamine transporter protein appears to contribute to the survival of lung cancer cells, suggesting it may be a useful diagnostic biomarker and target for therapies. Read MoreOctober 5, 2015
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The yin and yang of COX-2
New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs. Read MoreOctober 2, 2015
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Tolerating a transplant
A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease. Read MoreOctober 1, 2015
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Data diving for health
To most effectively use electronic health records for research, investigators should query multiple components of the record to identify patients with specific diseases. Read MoreSeptember 23, 2015
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Nerve cell remodelers
Vanderbilt investigators have defined a gene expression program that controls the timing of synaptic remodeling – a process that is critical to brain development, learning and memory. Read MoreSeptember 18, 2015
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Heart repair factor
A signaling factor called Wnt10b is a novel target for optimizing cardiac repair after a heart attack. Read MoreSeptember 17, 2015
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Study shows lower systolic BP targets reduce death risk
The initial results of a landmark clinical trial sponsored by the National Institutes of Health (NIH) indicate lowering systolic blood pressure below a commonly recommended target significantly reduces rates of cardiovascular events and lowers risk of death in a group of adults 50 years and older. Read MoreSeptember 17, 2015
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Grants spur effort to add genetic data to EMR
Vanderbilt University researchers have received two major federal grants — totaling $7.6 million over four years — to support groundbreaking research aimed at making genetic information a routine part of patients’ electronic medical records. Read MoreSeptember 10, 2015
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How to build a basement
Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer. Read MoreSeptember 9, 2015
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Vitamin C protects blood vessel lining
Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases. Read MoreSeptember 4, 2015