NIH
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Targeting the “un-targetable”
A novel drug that targets the protein RSK blocked aggressive breast cancers from metastasizing in an animal model. Read MoreNovember 18, 2016
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Stem cells promote tolerance
Blood-forming stem cells play a role in immune tolerance and acceptance of organ transplants, Vanderbilt researchers have discovered. Read MoreNovember 17, 2016
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Protein structure and epilepsy severity
Understanding how mutations affect the structure and function of inhibitory neurotransmitter receptors will shed light on the mechanisms underlying some types of epilepsy. Read MoreNovember 10, 2016
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Improving wound healing
Vanderbilt researchers have shown that an injectable material improves wound healing and may be useful for large skin wounds such as those in patients with diabetes. Read MoreNovember 8, 2016
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Early study finds antibody that ‘neutralizes’ Zika virus
Researchers at Vanderbilt University Medical Center and Washington University School of Medicine in St. Louis have isolated a human monoclonal antibody that in a mouse model “markedly reduced” infection by the Zika virus. Read MoreNovember 7, 2016
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VUMC investigators find pathogens work together to infect host
Pseudomonas aeruginosa and Staphylococcus aureus — two pathogens that frequently co-infect the lungs of patients with cystic fibrosis — appear to cooperate with each other, Vanderbilt investigators have discovered. When pseudomonas is starved for metal by the host, it shuts down the production of factors that would normally kill staph, promoting a co-infection. Read MoreNovember 3, 2016
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A DARPP role in gastric cancer
Vanderbilt researchers have discovered a link between Helicobacter pylori infection, inflammation and gastric cancer that could suggest new anti-cancer therapies. Read MoreNovember 3, 2016
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Bioluminescent sensor causes brain cells to glow in the dark
A team of Vanderbilt scientists have genetically modified luciferase, the enzyme that produces bioluminescence, so that it acts as an optical sensor that records activity in brain cells. Read MoreOctober 27, 2016
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Single-cell study of tumor samples
A new method for analyzing cells in fixed biopsy tissues from patients by guide personalized treatment strategies for cancer. Read MoreOctober 26, 2016
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Sleep issues in children with diabetes
Lengthening sleep duration and reducing sleep disturbances in children with type 1 diabetes may improve diabetes outcomes and reduce parental stress. Read MoreOctober 24, 2016