NIH
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New clues emerge in rare form of childhood epilepsy
Researchers at Vanderbilt University Medical Center (VUMC) are one step closer to understanding what causes early-onset epileptic encephalopathy, a rare form of childhood epilepsy that is difficult to treat and has poor developmental outcomes. Read MoreDecember 15, 2016
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Faster (cheaper) method for making big bioactive ring molecules
A pair of Vanderbilt chemists have developed a faster, cheaper method for synthesizing ring molecules called cyclic depsipeptides found in antibiotics, anti-retrovirals and pesticides. Read MoreDecember 12, 2016
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Single-cell analysis of solid tumors
A new method will make it possible to study solid tumors and healthy tissues using mass cytometry. Read MoreDecember 12, 2016
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Protecting the blood-brain barrier
Vanderbilt investigators have discovered how a promising cancer immunotherapy causes brain swelling, findings that could lead to ways to protect brain function while fighting cancers. Read MoreDecember 9, 2016
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Making human beta cells reproduce
A new method developed at Vanderbilt will speed the search for potential therapeutics for diabetes: compounds that stimulate the replication of insulin-producing beta cells. Read MoreDecember 8, 2016
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Plasmin prevents muscle ‘hardening’ after injury: study
Vanderbilt researchers have made the surprising discovery that the protease plasmin, known for its clot-busting role in the blood, protects soft tissue from turning to bone after severe injuries and certain orthopaedic surgeries. Read MoreDecember 8, 2016
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Blood-brain barrier on a chip sheds new light on “silent killer”
A new microfluidic device containing human cells that faithfully mimics the behavior of the blood-brain barrier is providing new insights into brain inflammation, the silent killer. Read MoreDecember 6, 2016
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Study tests shorter antibiotic course in children
Researchers at Vanderbilt University Medical Center (VUMC) are leading a multicenter clinical trial to evaluate whether a shorter course of antibiotics — five days instead of 10 — is effective at treating community-acquired pneumonia (CAP) in children who show improvement after the first few days of taking antibiotics. Read MoreDecember 1, 2016
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Reducing antidepressants’ side effects
Vanderbilt investigators have discovered how antidepressant medicines that block serotonin uptake can increase bleeding risk. Read MoreNovember 23, 2016
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Building the basement membrane
Vanderbilt researchers have discovered steps in the regulation of a key enzyme that builds the basement membrane, a structure that undergirds nearly all animal tissues. Read MoreNovember 21, 2016