Inflammation
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Therapeutic target for gastric cancer
A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies. Read MoreDecember 12, 2013
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New target for stopping inflammation
Importin alpha 5, a member of a family of proteins that “shuttle” other proteins into the nucleus, is a potential new target for drugs to treat inflammatory diseases. Read MoreOctober 11, 2013
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‘Yo-yo dieting’ inflames fat tissue
Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone. Read MoreAugust 9, 2013
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Nuclear shield against cell death
The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold. Read MoreAugust 8, 2013
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Bacterial signals in sarcoidosis
Study adds evidence for infectious agents’ role in sarcoidosis, an inflammatory condition that can lead to respiratory failure and death. Read MoreNovember 6, 2012
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How ‘Jedi’ disposes of dead neurons
The protein Syk is essential for clearing away neuron “corpses” in the developing peripheral nervous system. Read MoreSeptember 19, 2012
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Low oxygen could protect sick kidneys
Low oxygen – and the activation of factors that respond to this situation – may be protective in chronic kidney disease. Read MoreJune 28, 2012
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Vanderbilt research finds immune cells fan flames of obesity-related inflammation
Researchers at Vanderbilt University have discovered that an unusual set of immune cells, called invariant natural killer T cells, can exacerbate obesity-related inflammation. Read MoreApril 10, 2012
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Plant compound quells inflammation
Berberine, an herbal remedy for diarrhea and intestinal parasites, may be an effective treatment for gastrointestinal inflammatory diseases. Read MoreApril 6, 2012
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Enzyme protects against inflamed colon
Increasing an enzyme required for a type of colon tissue may help dampen inflammation, a known risk factor for colon cancer. Read MoreMarch 7, 2011