Inflammation

New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells. Read More

Heather Pua, MD, PhD, one of 60 investigators to receive the 2019 NIH Director’s New Innovator Award, will explore a novel type of cell signaling by RNAs in allergic airway inflammation. Read More

A new study published by Vanderbilt mechanobiology researchers details a possible solution for fine-tuning inflammation and cellular activity in cardiac recovery – thanks to an antibody initially developed for rheumatoid arthritis.  Read More

Investigators are exploring the molecular mechanisms behind the association of chronic inflammation and colon cancer. Read More

A previously unrecognized role for a cell surface receptor may open new therapeutic options for the treatment of fibrotic diseases. Read More

Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases. Read More

Inhibiting COX-2 — an enzyme associated with inflammation — could provide a novel therapeutic approach for stress-related psychiatric disorders. Read More

An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection. Read More

Vanderbilt researchers have discovered that curcumin — the active ingredient in the spice turmeric — needs to be metabolically activated to exert anti-inflammatory effects. Read More

New findings from Vanderbilt suggest that blocking the migration of cells involved in asthma may represent a new approach for treating the respiratory condition. Read More