Bacteria
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Probing innate immunity
Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA. Read MoreMay 19, 2020
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A probiotic treatment for obesity?
Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases. Read MoreAugust 8, 2019
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Mouth health and colorectal cancer
Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC. Read MoreJune 6, 2019
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Insect gene allows reproductive organs to cope with harmful bacteria
Bordenstein’s team studied Nasonia parasitic wasps, which are about the size of a sesame seed, and they serve as one of the best models to dissect and characterize the evolution of insect genomes. Read MoreMay 17, 2018
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Lighting up iron levels
A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease. Read MoreJanuary 11, 2018
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Sugars in human mother’s milk are non-toxic antibacterial agents
A new study has found that sugars in mother's' milk do not just provide nutrition for babies but also help protect them from bacterial infections. Read MoreAugust 20, 2017
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Predicting the infection response
Vanderbilt investigators are probing the response to a bacterial toxin as a clinical assessment of immune function. Read MoreApril 19, 2017
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Bacterial signaling systems
Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance. Read MoreFebruary 3, 2017
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Slight chemical change may improve TB treatments: study
One small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis, Vanderbilt researchers have discovered. Read MoreFebruary 11, 2016
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Immune tolerance in endothelial cells
Inducing “tolerance” to bacterial toxins in the endothelial cells that line blood vessels may offer a new approach for preventing the negative consequences of sepsis. Read MoreJanuary 7, 2016