Bacteria
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Vanderbilt chemist part of major microbiome research initiative
Vanderbilt chemist helps craft call for major new research initiative to increase our understanding of the invisible world of microbes that surround us. Read MoreNovember 4, 2015
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Detect and defend against pathogens
Understanding factors, such as the receptor TLR9, that detect and defend against pathogens may lead to therapeutic approaches that promote an effective immune response to treat infections. Read MoreNovember 4, 2015
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Study identifies C. diff toxin receptor, suggests new treatment approaches
Vanderbilt University investigators have identified a cellular receptor for a toxin from Clostridium difficile (“C. diff”) — the leading cause of hospital-acquired diarrhea in the United States. Read MoreJune 4, 2015
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Preventing early pregnancy complications
The enzyme alkaline phosphatase may provide a new therapeutic option for women at high risk of pregnancy complications due to bacterial toxin exposure. Read MoreMay 20, 2015
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Early human populations may have been shaped by bacteria the body hosts
Vanderbilt mathematician Glenn Webb and NYU microbiologist Martin Blaser propose that the microbes which live on our bodies may have influenced the age structure of human populations in prehistoric times. Read MoreDecember 16, 2014
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Bacterial secretion machinery: 3-D view
New structural findings reveal how "gatekeeper" proteins participate in the secretion systems bacteria use to infect host cells. Read MoreDecember 11, 2014
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Peptide quells “genomic storm”
A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection. Read MoreOctober 28, 2014
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Anthrax bacteria’s signaling systems
Vanderbilt researchers have identified a new signaling system that anthrax bacteria uses to infect its host. Read MoreApril 15, 2014
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Bacterial resistance breaks bridges
Understanding how bacteria become resistant to quinolone antibiotics could guide strategies for developing new antibacterial drugs. Read MoreMarch 14, 2013
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Antibacterial protein’s molecular workings revealed
Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require. Read MoreFebruary 21, 2013