Current Opportunities at Vanderbilt

The Alexander Lab, part of the Department of Medicine at Vanderbilt University Medical Center, is seeking applications for a postdoctoral fellow position. Research involves understanding the role of immune cells in the pathogenesis of hypertension and related end-organ damage. Applicant requirements: MD or Ph.D. in discipline related to cardiovascular disease or immunology preferred. First-author publication(s) and demonstrated skills in communication, scientific writing, and laboratory skills such as cell culture, mouse models of disease, flow cytometry, and related techniques are preferred.

Department Medicine: Clinical Pharmacology/Cardiovascular Medicine
Full Description

A position for a postdoctoral fellow is available in the Alexander laboratory in the Department of Medicine and Divisions of Clinical Pharmacology and Cardiovascular Medicine. Our laboratory performs basic/translational research that obtains initial insights from human disease and uses reductionist approaches including mouse models and cell culture to understand mechanisms and develop targeted therapies. Research projects include i) determining the role of unique regulatory T cell subsets in the pathogenesis of hypertension and end-organ damage, ii) determining the role of neutrophil production by the bone marrow in blood pressure elevations and renal damage in psoriasis, and iii) determining mechanisms of increased inflammation in patients with low renin low aldosterone hypertension, and iv) determining the role of regulatory T cells in pre-eclampsia and increased postpartum hypertension risk. Studies utilize cell culture, in vivo mouse models, and translational human studies with cutting edge approaches including single cell RNA sequencing, spectral flow cytometry, microvascular function evaluation, and endothelial cell stretch. The postdoctoral fellow will be part of a dynamic research group with excellent mentoring and opportunities for career advancement. The Alexander lab will provide opportunities to learn new skills, work with a diverse group of scientists and clinicians, and share your work in conferences and publications. 

Ideal candidates will be self-motivated with good interpersonal and communication skills and have experience and interest in cardiovascular disease and/or immunology.

Application Details

Please email a cover letter and CV to Matt Alexander, M.D., Ph.D. at The cover letter should describe: 1) prior research experience, 2) research interests, 3) career goals, and 4) contact information for three references.

Contact Matt Alexander
Posted 2024-05-22 19:03:36

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