Virus
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Probing innate immunity
Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA. Read MoreMay 19, 2020
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Antibodies eye Pacific Island “fever”
Vanderbilt Vaccine Center team isolates monoclonal antibodies against the mosquito-borne Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months. Read MoreMay 14, 2020
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Evolution of a deadly virus
Genomic sequences have revealed that Florida is a major source of a mosquito-borne virus that causes disease in horses and humans. Read MoreMay 23, 2018
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New target to stop Ebola
A new Vanderbilt study suggests it may be possible to develop antibody therapies or a universal vaccine effective against multiple Ebola virus family members. Read MoreMay 21, 2018
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Alphavirus “Achilles heel”
Targeting the protein that mosquito-borne viruses use to enter cells could be a strategy for preventing infection by multiple emerging viruses. Read MoreMay 17, 2018
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Enzyme holds the door for influenza
Compounds developed at Vanderbilt University may offer a new way to block influenza infection. Read MoreAugust 20, 2014
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Natural killer cells don’t clear HMPV
Understanding how the immune system responds to the respiratory virus HMPV is crucial for developing vaccines and anti-viral treatments. Read MoreJuly 23, 2014
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Respiratory virus vaccine candidate
Virus-like particles containing a protein from human metapneumovirus are a promising vaccine candidate for this respiratory virus. Read MoreMay 27, 2014
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Target cell entry to halt Chikungunya virus
Understanding how chikungunya virus binds to and enters cells offers a new target for antiviral medications. Read MoreApril 28, 2014
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Grant targets new therapies for Ebola, Marburg viruses
Vanderbilt’s James Crowe Jr., M.D., and a collaborator in Texas have been awarded a $4.4 million grant from the U.S. Department of Defense to study new ways to treat and prevent Ebola and Marburg viruses. Read MoreMay 16, 2013