RNA
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Vanderbilt scientists receive National Science Foundation grant to explore RNA behavior
Manuel Ascano, associate professor of biochemistry and pathology, microbiology and immunology, and Dr. Alissa Weaver, Cornelius Vanderbilt Chair and director of the Vanderbilt Center for Extracellular Vesicle Research, are one of nine U.S. research teams awarded funding from the National Science Foundation to more fully understand the potential biotechnological uses of RNA, ranging from crop disease protection to treatments that combat cancer. Read MoreMarch 18, 2024
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Study details RNA editing in virus-infected cancer cells
Vanderbilt researchers detail the landscape of RNA editing — a form of RNA modification — in primary effusion lymphoma cells during Kaposi’s sarcoma-associated herpesvirus infection and identify an edited viral microRNA that is critical for infection. Read MoreApril 20, 2023
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Cellular antiviral defenses
A cellular RNA quality control mechanism was known to restrict replication of RNA viruses. Vanderbilt researchers have discovered it is also antiviral against DNA viruses. Read MoreJuly 23, 2020
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Cellular factor helps package flu genome
New insights on influenza genome packaging could guide strategies for interfering with the virus's life cycle and ability to cause infection. Read MoreApril 8, 2020
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Pua lands NIH Director’s New Innovator Award
Heather Pua, MD, PhD, one of 60 investigators to receive the 2019 NIH Director’s New Innovator Award, will explore a novel type of cell signaling by RNAs in allergic airway inflammation. Read MoreOctober 1, 2019
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Probing the genetics of autoimmunity
Vanderbilt researchers have found that non-coding regions of the genome appear to contribute to the risk of autoimmune diseases and may represent attractive therapeutic targets. Read MoreJuly 21, 2017
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A molecular clue to longevity
In budding yeast, accumulation of a certain type of RNA in the nucleus increased life span, offering a new clue to longevity. Read MoreMarch 31, 2017
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Possible overeating antidote
The 2C-subtype of the serotonin receptor (5HT2C), which binds the neurotransmitter serotonin, plays an important role in regulating food intake and metabolism. Read MoreAugust 1, 2016
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RNA defects in multiple sclerosis
Vanderbilt researchers have discovered that profound defects exist in the integrity of structural RNA molecules in patients with relapsing remitting multiple sclerosis. Read MoreApril 30, 2015
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Micelle “packets” deliver cancer drugs
Vanderbilt researchers designed micelle “packets” to selectively deliver anti-cancer drugs to breast cancer cells. Read MoreApril 8, 2015