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New insights into hypothalamic obesity
A common Type 2 diabetes treatment being tested for hypothalamic obesity had unexpected results on weight loss and total energy expenditure, Vanderbilt researchers report. Read MoreFebruary 10, 2022
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Omicron evades some but not all monoclonal antibodies: study
A new study found that several, but not all, of the human monoclonal antibodies used clinically to prevent patients from becoming severely ill from COVID-19 may not be protective against the Omicron variant now sweeping across the United States. Read MoreJanuary 20, 2022
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New way to bEET insulin resistance
Signaling molecules called EETs could improve insulin resistance, a primary risk factor for Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered. Read MoreNovember 11, 2021
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The challenge of rejection
Minimizing variation in how rejection is diagnosed and creating standardized surveillance protocols may help inform best practices in pediatric heart transplants. Read MoreNovember 10, 2021
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VUMC researchers a step closer to broad ebolavirus protection
A combination of two broadly acting monoclonal antibodies isolated by researchers at Vanderbilt University Medical Center protected non-human primates from ebolavirus disease, which causes severe and often-fatal hemorrhagic fever in humans. Read MoreNovember 10, 2021
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Study explores concussion recovery by race
Vanderbilt researchers are exploring the outcomes and experiences of Black and White athletes following a sports-related concussion. Read MoreSeptember 23, 2021
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White matter and schizophrenia
Patients with schizophrenia have functional changes in the white matter of the brain, Vanderbilt researchers have discovered, which may contribute to impaired working memory and processing speed. Read MoreSeptember 2, 2021
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Rheumatoid arthritis drug combined with standard of care may help reduce mortality for hospitalized COVID-19 patients
Hospitalized patients with COVID-19 who received the rheumatoid arthritis drug baricitinib, in combination with the standard of care including corticosteroids, died less often than those receiving only the standard of care, according to a study released this week. Read MoreSeptember 2, 2021
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Discovery offers insight for development of cancer therapies targeting mutant p53
The tumor suppressor protein p53 is mutated in more than half of all human cancers. Several drugs that potentially can restore mutant p53 to its normal cancer-killing function are in clinical investigation. Read MoreSeptember 2, 2021
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Team isolates antibodies that target alphaviruses
A multi-institutional team led by researchers at Vanderbilt University Medical Center has isolated monoclonal antibodies that prevent infection by alphaviruses, including the often-lethal Eastern equine encephalitis virus. Read MoreAugust 19, 2021