Microtubules
-
The plus and minus of microtubules
Understanding the dynamic regulation of cytoskeletal microtubules may suggest new ways to treat disorders ranging from Alzheimer's disease to cancer. Read MoreSeptember 5, 2019
-
New role for microtubules in diabetes
Microtubules, part of the cell's cytoskeleton, regulate the secretion of insulin, suggesting that they may be a new target for treating diabetes. Read MoreJuly 29, 2019
-
Cell skeleton and the brush border
Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines. Read MoreJanuary 31, 2018
-
Research sheds light on how microtubules are assembled
Microtubules are the “railroad tracks” essential for moving intracellular “freight” around in the cell. They’re also part of the spindle that pulls the two centrosomes apart during cell division. Read MoreJanuary 4, 2018
-
Microtubules act as cellular ‘rheostat’ to control insulin secretion
Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell. Read MoreDecember 3, 2015
-
Zanic’s journey to the lab followed winding path
It’s roughly 5,000 miles from Croatia to Tennessee as the crow flies. Read MoreMarch 5, 2015
-
VU study reveals factor’s new role in cell division, migration
Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery. Read MoreOctober 30, 2014