Matthew Tyska

Researchers at four institutions, including Vanderbilt, have been awarded a five-year, $9.4 million federal grant to tackle undiagnosed congenital diarrheas caused by a single gene mutation. Read More

Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border. Read More

Matthew Tyska and colleagues have found that an adhesion protein in the gut is necessary for proper intestinal functioning. Read More

Research led by Matthew Tyska gives new insight into the formation of the lining of the gut that helps us absorb nutrients and guard against illness. Read More

Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines. Read More

New findings implicate a motor protein in the assembly of the brush border in the intestines and kidneys – a specialized surface that is critical for healthy organ function. Read More

Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease. Read More

Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens. Read More

Two new “super-resolution” optical microscopes have put Vanderbilt University Medical Center on the cutting edge of cellular imaging, and are giving researchers their first views of the cell at the molecular level. Read More

The epithelial cells that line the intestines have a newly discovered mechanism for protecting us against microbes: they fire anti-bacterial "bullets" into the gut. Read More