JCI Insight

Vanderbilt investigators have discovered that vasopressin, which has long been thought to be produced only in the brain, is also produced in the kidney. Read More

Vanderbilt research has revealed an important mechanism in the kidney by which a cell surface receptor known as DDR1 fans the flames of inflammation and fibrosis that ultimately lead to kidney failure. Read More

Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it. Read More

Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at VUMC have discovered. Read More

Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at VUMC have discovered. Read More

A new imaging method makes it possible to directly measure cell division and changes in metabolism in atherosclerotic plaques. Read More

Investigators at Vanderbilt-Ingram Cancer Center (VICC) and the Virginia Tech Carilion Research Institute (VTCRI) have revealed a gene mutation’s role in Von Hippel-Lindau syndrome, a genetically inherited disease which causes tumor growth in several organs. Read More

Acetaminophen may offer a simple treatment to prevent tissue injury following lung transplant, Vanderbilt researchers have discovered. Read More

Researchers in the Schools of Medicine and Engineering at Vanderbilt University have discovered a proteomic “signature” from the airways of heavy smokers that could lead to better risk assessment and perhaps new ways to stop lung cancer before it starts. Read More