Imported-post
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C.diff captures blood cell cofactor to build defensive shield
Vanderbilt University Medical Center scientists have identified a C. diff protein system that senses and captures heme (part of hemoglobin) to build a protective shield that fends off threats from our immune system and antibiotics. Read MoreJune 10, 2020
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Vanderbilt, AstraZeneca sign new COVID-19 antibody agreement
After evaluating the ability of more than 1,500 monoclonal antibodies to bind and neutralize the COVID-19 virus, SARS-CoV-2, in the laboratory, AstraZeneca signed an exclusive license to six candidate antibodies in Vanderbilt’s portfolio. Read MoreJune 9, 2020
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Protecting the injured kidney
Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it. Read MoreJune 4, 2020
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Potential new cancer target
Vanderbilt researchers have discovered the involvement of a certain type of adenosine receptor in mediating signaling that supports tumor growth and metastasis. Read MoreJune 4, 2020
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Remdesivir helps reduce COVID-19 recovery time: study
The investigational antiviral drug remdesivir can shorten the time to recovery in adults hospitalized with COVID-19, according to preliminary results of a clinical trial published last month in The New England Journal of Medicine. Read MoreJune 4, 2020
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VUMC research ramps up in COVID-19 transition
As Nashville cautiously begins to emerge from its two-month-long COVID-19 Safer at Home response, so too are the labs and facilities at Vanderbilt University Medical Center. Read MoreMay 21, 2020
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Team uses imaging to study ways the heart is affected by coronavirus
Researchers are using imaging and diagnostic pathology to examine postmortem hearts donated by victims of COVID-19 to gain a better understanding of how the coronavirus that causes COVID-19 affects the heart. Read MoreMay 21, 2020
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VUMC Research Enterprise begins ramping up
As Nashville cautiously begins to emerge from its two-month-long COVID-19 Safer at Home response, so too are the labs and facilities at Vanderbilt University Medical Center. Read MoreMay 19, 2020
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Probing innate immunity
Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA. Read MoreMay 19, 2020