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NSF seed grant supports biomanufacturing of new drug delivery technologies
Vanderbilt researchers awarded one of NSF’s 24 new projects to drive future manufacturing One of the challenges of drug delivery systems is to optimize their targeting properties so therapeutic compounds used in smaller amounts reach only a specific area of the body and result in little or no side effects. The ability to engineer the... Read MoreOctober 2, 2020
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Study identifies antibodies that block alphaviruses
Researchers at Vanderbilt University Medical Center have identified antibodies that, in animals, block infection by alphaviruses, which can cause chronic and debilitating joint pain and arthritis and are an increasing global health concern. Read MoreSeptember 20, 2020
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VUMC awarded $34 million to lead nationwide convalescent plasma study
Vanderbilt University Medical Center has been awarded a one-year, $34-million grant by the National Center for Advancing Translational Sciences, part of the National Institutes of Health, to conduct a nationwide study of “convalescent plasma” as a treatment for COVID-19. Read MoreSeptember 20, 2020
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‘Scavenger’ molecule may point to new atherosclerosis treatment
A small-molecule “scavenger” that reduces inflammation and formation of atherosclerotic plaque in blood vessels in mice potentially could lead to a new approach for treating atherosclerosis in humans, according to researchers at Vanderbilt University Medical Center. Read MoreSeptember 20, 2020
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Sin3a regulates pancreatic β-cells fitness and function
The transcriptional coregulator Swi-independent 3 — or Sin3 — switches on and off the genes that drive crucial biological processes during prenatal development, including cellular differentiation, maturation, survival, metabolism, and stress responses. Read MoreSeptember 14, 2020
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Myosin motors regulate cell shape during division
When a bouncy ball deforms under the weight of your body, its rubber membrane stretches and contracts. Likewise, the membrane of a cell doubling itself prior to division must accommodate changes in intracellular pressure — or explode. Read MoreSeptember 14, 2020
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VIR-CLASP reveals new insights into cellular mechanisms of viral immune response
RNA viruses invade cells and co-opt cellular machinery to replicate and translate their genomic material. Read MoreSeptember 10, 2020
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Study explores the role of MYCN in Triple Negative Breast Cancer diagnosis and treatment
The oncogene MYCN regulates cancer cell growth, proliferation, metabolism, and survival; tumors with increased MYCN expression are more aggressive. Read MoreSeptember 10, 2020
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Grissom awarded $1.4 million NIH grant to develop smaller, quieter MRI system
Vanderbilt engineers have received a $1.4 million NIH grant to work toward a compact, silent, less expensive and potentially portable MRI device. Read MoreSeptember 1, 2020
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Vip1 allows cells to adapt to changing conditions
Research shows how the actions of Vip1 help cells change their shape in response to environmental conditions. Read MoreAugust 28, 2020