Immune Response

A new technique will allow researchers to track subsets of immune cells that patrol and defend the lungs, to better understand the roles of these cells during lung inflammation, infection and injury. Read More

New Vanderbilt research could inform therapeutic strategies for enhancing thymic function when desired — such as during aging, recovery from radiation therapy or chemotherapy, or other conditions that reduce T cell output. Read More

Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA. Read More

Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases. Read More

New research links nutrient-responsive cellular signaling to the antibody-mediated immune response. Read More

Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies. Read More

Scott Smith, M.D., Ph.D., assistant professor of Medicine, has received a 2017 research award from the Stanley Cohen Innovation Fund to test a new therapeutic strategy for peanut allergies. Smith's research could fundamentally change allergy treatment. Read More

Too much dietary manganese — an essential trace mineral found in leafy green vegetables, fruits and nuts — promotes infection of the heart by the bacterium Staphylococcus aureus (“staph”). Read More

Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease. Read More

Vanderbilt investigators have conducted a first-of-its-kind genome-wide association study of lung cancer survival in African-Americans. Read More