Heart

To study the dynamics of structural proteins in the heart, Vanderbilt investigators generated a cellular tool they expect will be useful for screening drugs that affect heart muscle contraction. Read More

Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease. Read More

A metabolic change in adult stem cells makes them less “fit” for regenerative heart therapies, suggesting that strategies to prevent this response may boost the therapeutic usefulness of the cells. Read More

Vanderbilt researchers have identified a new protein involved in heart cell growth, which could improve understanding of pathologic cardiac hypertrophy. Read More

Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, Vanderbilt University investigators have discovered. Read More

Smooth muscle cells that line the aorta differ in development but not in the adult, a finding that has implications for understanding aortic development and disease. Read More

A “profile” of the genes and regulatory networks that govern early heart valve development lay the groundwork for generating valves from a patient’s own cells. Read More

A protein that connects cells together participates in the calcification that occurs in heart valve disease. Read More

An unexpected group of cells generates the coronary arteries and may be useful for regeneration therapies following injury to the heart. Read More

Blocking a serotonin receptor may provide a novel therapy for heart valve disease. Read More