HDL

A new model suggests that a protein involved in the generation of high-density lipoprotein (HDL) works differently than previously thought. Read More

Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins. Read More

Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis. Read More

Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy. Read More

Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease. Read More

Structural features of newly formed HDL particles will help guide understanding of “good cholesterol” and its function. Read More

Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered. Read More

Chronic kidney disease impairs the protective functions of HDL, Vanderbilt researchers report this month. Read More

In some cases, HDL, the "good cholesterol," may not function properly and may actually accelerate atherosclerosis. Read More

HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk. Read More